SYRE in the 13F filings
Spyre Therapeutics Inc · CUSIP 00773J202
- Quarter end
- 31 Dec 2024
- the date the book describes
- Filed
- 14 Feb 2025
- latest of these filings; the earliest 13 Feb 2025
- Managers listing it
- 4
- at least, of 95 tracked, among listed positions
- Comparable managers
- 94
- filed both Q3 2024 and Q4 2024; 3 listed it in both
- Shares listed
- 2,437,993
- combined, among listed positions
- Reported value
- $57m
- combined, at the quarter end
Among the 94 comparable managers: 4 buyers (opened or added shares) and 0 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +908,206.
Managers listing SYRE in Q4 2024
4 of 4 holders
| Action | Filing | |||||
|---|---|---|---|---|---|---|
| Janus Henderson Group Ltd | 1,456,740 | $34m | under 0.1% | Added | +336,209 | 14 Feb 2025 (the filing on sec.gov) |
| Capital World Investors | 378,573 | $8.8m | under 0.1% | New | new | 13 Feb 2025 (the filing on sec.gov) |
| Woodline Partners LP | 352,680 | $8.2m | 0.06% | Added | +88,424 | 14 Feb 2025 (the filing on sec.gov) |
| Soros Fund Management LLC | 250,000 | $5.8m | 0.09% | Added | +105,000 | 14 Feb 2025 (the filing on sec.gov) |
Largest increases and reductions, by shares
Increases
- Capital World Investorsnew position · 378,573 shares now+378,573
- Janus Henderson Group Ltdexisting position · 1,456,740 shares now+336,209
- Soros Fund Management LLCexisting position · 250,000 shares now+105,000
- Woodline Partners LPexisting position · 352,680 shares now+88,424
Reductions
No reduction among listed positions.
New positions and exits
New (1)
Exited (0)
No exit shown by a manager’s own filing.
Ownership over time
Tracked managers listing it, at least.
| Quarter | Holders | Reported value | Buyers | Sellers |
|---|---|---|---|---|
| Q1 2024 | 3 | $23m | 3 | 0 |
| Q2 2024 | 3 | $25m | 3 | 0 |
| Q3 2024 | 3 | $45m | 2 | 1 |
| Q4 2024 | 4 | $57m | 4 | 0 |
| Q1 2025 | 3 | $15m | 1 | 2 |
| Q4 2025 | 2 | $69m | 13 | 8 |
| Q1 2026 | 5 | $729m | 12 | 7 |
| Q2 2026 | 9 | $2.2bn | 23 | 6 |
Compare with…
Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.
SYRE and LLY →SYRE and JNJ →SYRE and VRTX →Choose a stock to compare with SYRE →
How much of the picture this is
A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.
Which funds own SYRE, latest filings →Back to the 13F Explorer →