L3VLUP
Quarter end
30 Jun 2025
the date the book describes
Filed
14 Aug 2025
latest of these filings; the earliest 6 Aug 2025
Managers listing it
22
at least, of 95 tracked, among listed positions
Comparable managers
95
filed both Q1 2025 and Q2 2025; 14 listed it in both
Shares listed
56,189,777
combined, among listed positions
Reported value
$18.3bn
combined, at the quarter end

Among the 95 comparable managers: 13 buyers (opened or added shares) and 10 sellers (trimmed or exited), at least, among listed positions. Their net change in shares is not known from listed positions, because at least one of them lists it in only one of the two quarters.

Managers listing ALNY in Q2 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q1 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

22 of 22 holders

ActionFiling
Capital World Investors16,805,007$5.5bn0.80%Added+55,38413 Aug 2025 (the filing on sec.gov)
Fidelity (FMR LLC)15,806,521$5.2bn0.29%Added+496,66114 Aug 2025 (the filing on sec.gov)
Capital Research Global Investors7,191,656$2.3bn0.47%Added+36,92813 Aug 2025 (the filing on sec.gov)
Dodge & Cox3,197,096$1.0bn0.59%Trimmed-154,66613 Aug 2025 (the filing on sec.gov)
T. Rowe Price Associates Inc3,145,006$1.0bn0.12%Trimmed-360,16214 Aug 2025 (the filing on sec.gov)
Baillie Gifford & Co3,031,891$989m0.74%Trimmed-625,7166 Aug 2025 (the filing on sec.gov)
Wellington Management Group LLP2,075,752$677m0.12%Trimmed-535,23414 Aug 2025 (the filing on sec.gov)
Invesco Ltd1,341,694$438m0.07%Addedn.a.13 Aug 2025 (the filing on sec.gov)
Woodline Partners LP623,115$203m1.07%Added+466,65114 Aug 2025 (the filing on sec.gov)
Citadel Advisors LLC601,199$196munder 0.1%Addedn.a.14 Aug 2025 (the filing on sec.gov)
Holocene Advisors LP596,816$195m0.47%Newnew14 Aug 2025 (the filing on sec.gov)
Two Sigma Investments LP343,305$112m0.20%Added+145,89014 Aug 2025 (the filing on sec.gov)
Two Sigma Advisers LP266,100$87m0.18%Trimmed-9,70014 Aug 2025 (the filing on sec.gov)
Marshall Wace LLP238,573$78m0.09%Trimmed-30,35913 Aug 2025 (the filing on sec.gov)
Point72 Asset Management LP201,396$66m0.13%Trimmed-99,23914 Aug 2025 (the filing on sec.gov)
AQR Capital Management LLC188,249$61m0.05%Trimmed-640,09514 Aug 2025 (the filing on sec.gov)
Arrowstreet Capital LP169,700$55munder 0.1%Addedn.a.13 Aug 2025 (the filing on sec.gov)
Janus Henderson Group Ltd150,421$49munder 0.1%Trimmed-31,22814 Aug 2025 (the filing on sec.gov)
Balyasny Asset Management LLC115,275$38m0.06%Addedn.a.14 Aug 2025 (the filing on sec.gov)
Schonfeld Strategic Advisors LLC58,757$19m0.13%Addedn.a.14 Aug 2025 (the filing on sec.gov)
Walleye Capital LLC38,715$13munder 0.1%Addedn.a.13 Aug 2025 (the filing on sec.gov)
Winton Group Ltd3,533$1.2m0.06%Newnew14 Aug 2025 (the filing on sec.gov)

Largest increases and reductions, by shares

Q1 2025 to Q2 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
18 in Q3 2024 to 21 in Q2 2026

Tracked managers listing it, at least.

0102030402014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
ALNY by quarter
QuarterHoldersReported valueBuyersSellers
Q2 20134$407mn.a.n.a.
Q3 20136$1.2bnn.a.n.a.
Q4 20137$1.5bnn.a.n.a.
Q1 20148$1.6bnn.a.n.a.
Q2 20146$1.7bnn.a.n.a.
Q3 20147$2.1bnn.a.n.a.
Q4 20146$2.2bnn.a.n.a.
Q1 20158$2.9bnn.a.n.a.
Q2 20156$3.3bnn.a.n.a.
Q3 20155$2.1bnn.a.n.a.
Q4 20156$2.7bnn.a.n.a.
Q1 20168$2.0bnn.a.n.a.
Q2 20167$2.0bnn.a.n.a.
Q3 20168$2.6bnn.a.n.a.
Q4 20168$1.6bnn.a.n.a.
Q1 20179$2.2bnn.a.n.a.
Q2 201714$3.8bnn.a.n.a.
Q3 201715$5.7bnn.a.n.a.
Q4 201714$6.3bnn.a.n.a.
Q1 201815$5.7bnn.a.n.a.
Q2 201815$4.4bnn.a.n.a.
Q3 201814$3.9bnn.a.n.a.
Q4 201810$3.3bnn.a.n.a.
Q1 201911$4.6bnn.a.n.a.
Q2 201916$3.8bnn.a.n.a.
Q3 201911$4.4bnn.a.n.a.
Q4 201913$6.2bnn.a.n.a.
Q1 202012$5.7bnn.a.n.a.
Q2 202015$7.7bnn.a.n.a.
Q3 202013$7.6bnn.a.n.a.
Q4 202013$6.5bnn.a.n.a.
Q1 202114$7.2bnn.a.n.a.
Q2 202113$8.8bnn.a.n.a.
Q3 202114$9.7bnn.a.n.a.
Q4 202112$8.8bnn.a.n.a.
Q1 202212$8.9bnn.a.n.a.
Q2 202213$8.1bnn.a.n.a.
Q3 202217$10.8bnn.a.n.a.
Q4 202216$13.7bnn.a.n.a.
Q1 202319$11.5bnn.a.n.a.
Q2 202316$10.6bnn.a.n.a.
Q3 202317$9.7bnn.a.n.a.
Q4 202315$10.0bn59
Q1 202415$7.3bn106
Q2 202419$12.5bn128
Q3 202418$15.1bn711
Q4 202415$12.8bn87
Q1 202518$14.9bn117
Q2 202522$18.3bn1310
Q3 202533$26.6bn258
Q4 202524$23.4bn1528
Q1 202622$17.9bn1618
Q2 202621$15.9bn1718

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

ALNY and LLY →ALNY and JNJ →ALNY and VRTX →Choose a stock to compare with ALNY →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own ALNY, latest filings →Back to the 13F Explorer →