L3VLUP
Quarter end
31 Mar 2026
the date the book describes
Filed
18 May 2026
latest of these filings; the earliest 12 May 2026
Managers listing it
22
at least, of 95 tracked, among listed positions
Comparable managers
91
filed both Q4 2025 and Q1 2026; 5 listed it in both
Shares listed
10,603,563
combined, among listed positions
Reported value
$173m
combined, at the quarter end

Among the 91 comparable managers: 12 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was -1,586,925.

Managers listing QURE in Q1 2026

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

22 of 22 holders

ActionFiling
Two Sigma Investments LP2,675,871$44munder 0.1%Added+1,224,58715 May 2026 (the filing on sec.gov)
Fidelity (FMR LLC)1,743,808$29munder 0.1%Trimmed-4,497,12815 May 2026 (the filing on sec.gov)
Susquehanna International Group LLP1,002,800$16munder 0.1%Trimmed-215,55015 May 2026 (the filing on sec.gov)
Balyasny Asset Management LLC964,290$16munder 0.1%Added+828,64615 May 2026 (the filing on sec.gov)
Millennium Management LLC792,756$13munder 0.1%Trimmed-10,84915 May 2026 (the filing on sec.gov)
Maverick Capital Ltd697,640$11m0.13%Added+35,82015 May 2026 (the filing on sec.gov)
Jane Street Group LLC635,995$10munder 0.1%Newnew12 May 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP436,467$7.1m0.06%Added+362,69214 May 2026 (the filing on sec.gov)
Citadel Advisors LLC404,565$6.6munder 0.1%Trimmed-64,73515 May 2026 (the filing on sec.gov)
Squarepoint Ops LLC345,983$5.7munder 0.1%Added+169,98315 May 2026 (the filing on sec.gov)
D. E. Shaw & Co.160,714$2.6munder 0.1%Added+28,75815 May 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP158,500$2.6munder 0.1%Added+33,00013 May 2026 (the filing on sec.gov)
Marshall Wace LLP122,736$2.0munder 0.1%Added+101,57715 May 2026 (the filing on sec.gov)
Moore Capital Management LP122,222$2.0munder 0.1%Added+47,22215 May 2026 (the filing on sec.gov)
Brevan Howard Capital Management LP108,632$1.8munder 0.1%Newnew15 May 2026 (the filing on sec.gov)
Walleye Capital LLC88,479$1.4munder 0.1%Added+9,48313 May 2026 (the filing on sec.gov)
Schonfeld Strategic Advisors LLC48,824$798kunder 0.1%Trimmed-73,70515 May 2026 (the filing on sec.gov)
Winton Group Ltd31,541$516kunder 0.1%Trimmed-16,64412 May 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc30,447$498kunder 0.1%Trimmed-178,19915 May 2026 (the filing on sec.gov)
Janus Henderson Group Ltd16,900$276kunder 0.1%Held018 May 2026 (the filing on sec.gov)
Farallon Capital Management LLC14,000$229kunder 0.1%Held015 May 2026 (the filing on sec.gov)
Quantbot Technologies LP393$6kunder 0.1%Trimmed-5,05113 May 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q4 2025 to Q1 2026, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
1 in Q3 2024 to 3 in Q2 2026

Tracked managers listing it, at least.

03581020142015201820192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
QURE by quarter
QuarterHoldersReported valueBuyersSellers
Q1 20141$779kn.a.n.a.
Q2 20142$5.5mn.a.n.a.
Q3 20142$3.7mn.a.n.a.
Q4 20141$5.2mn.a.n.a.
Q1 20151$2.2mn.a.n.a.
Q2 20151$15mn.a.n.a.
Q3 20151$11mn.a.n.a.
Q4 20151$7.7mn.a.n.a.
Q2 20161$4.1mn.a.n.a.
Q3 20161$4.5mn.a.n.a.
Q4 20171$2.7mn.a.n.a.
Q1 20181$3.2mn.a.n.a.
Q2 20181$669kn.a.n.a.
Q1 20191$1.0mn.a.n.a.
Q2 20195$49mn.a.n.a.
Q3 20197$54mn.a.n.a.
Q4 201910$581mn.a.n.a.
Q1 20205$258mn.a.n.a.
Q2 20208$143mn.a.n.a.
Q3 20206$144mn.a.n.a.
Q4 20207$90mn.a.n.a.
Q1 20215$117mn.a.n.a.
Q2 20215$103mn.a.n.a.
Q3 20215$69mn.a.n.a.
Q4 20213$48mn.a.n.a.
Q1 20223$66mn.a.n.a.
Q2 20225$94mn.a.n.a.
Q3 20223$111mn.a.n.a.
Q4 20224$50mn.a.n.a.
Q1 20237$47mn.a.n.a.
Q2 20234$9.4mn.a.n.a.
Q3 20234$8.2mn.a.n.a.
Q4 20233$4.0m11
Q1 20243$3.7m20
Q2 20243$4.5m20
Q3 20241$493k10
Q4 20245$57m41
Q1 20252$1.7m10
Q2 20252$2.6m10
Q3 20256$130m33
Q4 20256$80m1512
Q1 20264$21m1211
Q2 20263$111m1215

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

QURE and LLY →QURE and JNJ →QURE and VRTX →Choose a stock to compare with QURE →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own QURE, latest filings →Back to the 13F Explorer →