KRYS in the 13F filings
Krystal Biotech Inc · CUSIP 501147102
- Quarter end
- 31 Dec 2025
- the date the book describes
- Filed
- 27 Oct 2026
- latest of these filings; the earliest 10 Feb 2026
- Managers listing it
- 23
- at least, of 95 tracked, among listed positions
- Comparable managers
- 92
- filed both Q3 2025 and Q4 2025; 5 listed it in both
- Shares listed
- 6,807,930
- combined, among listed positions
- Reported value
- $1.7bn
- combined, at the quarter end
Among the 92 comparable managers: 13 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was -78,559.
Managers listing KRYS in Q4 2025
23 of 23 holders
Largest increases and reductions, by shares
Increases
- Janus Henderson Group Ltdexisting position · 219,440 shares now+209,369
- T. Rowe Price Associates Incexisting position · 529,955 shares now+62,897
- Marshall Wace LLPexisting position · 183,754 shares now+54,794
- Fidelity (FMR LLC)existing position · 4,349,628 shares now+8,181
- Renaissance Technologies LLCnew position · 3,300 shares now+3,300
Reductions
- Citadel Advisors LLCexisting position · 386,505 shares now-250,483
- Millennium Management LLCexisting position · 14,658 shares now-134,055
- Verition Fund Management LLCexisting position · 16,969 shares now-14,364
- Invesco Ltdexisting position · 60,008 shares now-6,872
- AQR Capital Management LLCexisting position · 14,157 shares now-5,976
New positions and exits
New (6)
Exited (3)
- Jane Street Group LLCwas $597k
- Man Group PLCwas $369k
- Freestone Grove Partners LPwas $359k
Ownership over time
Tracked managers listing it, at least.
| Quarter | Holders | Reported value | Buyers | Sellers |
|---|---|---|---|---|
| Q4 2018 | 1 | $260k | n.a. | n.a. |
| Q1 2019 | 1 | $581k | n.a. | n.a. |
| Q2 2019 | 1 | $2.5m | n.a. | n.a. |
| Q3 2019 | 1 | $2.4m | n.a. | n.a. |
| Q4 2019 | 1 | $1.3m | n.a. | n.a. |
| Q1 2020 | 2 | $15m | n.a. | n.a. |
| Q2 2020 | 4 | $45m | n.a. | n.a. |
| Q3 2020 | 4 | $52m | n.a. | n.a. |
| Q4 2020 | 3 | $66m | n.a. | n.a. |
| Q1 2021 | 3 | $67m | n.a. | n.a. |
| Q2 2021 | 2 | $28m | n.a. | n.a. |
| Q3 2021 | 2 | $31m | n.a. | n.a. |
| Q4 2021 | 2 | $135m | n.a. | n.a. |
| Q1 2022 | 1 | $114m | n.a. | n.a. |
| Q2 2022 | 2 | $107m | n.a. | n.a. |
| Q3 2022 | 3 | $97m | n.a. | n.a. |
| Q4 2022 | 3 | $59m | n.a. | n.a. |
| Q1 2023 | 3 | $59m | n.a. | n.a. |
| Q2 2023 | 3 | $82m | n.a. | n.a. |
| Q3 2023 | 5 | $143m | n.a. | n.a. |
| Q4 2023 | 5 | $109m | 3 | 1 |
| Q1 2024 | 8 | $853m | 5 | 2 |
| Q2 2024 | 6 | $1.0bn | 5 | 0 |
| Q3 2024 | 5 | $976m | 3 | 1 |
| Q4 2024 | 5 | $850m | 4 | 0 |
| Q1 2025 | 5 | $993m | 4 | 0 |
| Q2 2025 | 4 | $746m | 1 | 2 |
| Q3 2025 | 5 | $938m | 2 | 1 |
| Q4 2025 | 7 | $1.4bn | 13 | 11 |
| Q1 2026 | 6 | $1.5bn | 15 | 11 |
| Q2 2026 | 6 | $2.4bn | 12 | 14 |
Compare with…
Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.
KRYS and GILD →KRYS and AMGN →KRYS and ARGX →Choose a stock to compare with KRYS →
How much of the picture this is
A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.
Which funds own KRYS, latest filings →Back to the 13F Explorer →