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DNLI in the 13F filings

Denali Therapeutics Inc · CUSIP 24823R105

Sector · Pharmaceuticals and biotechnologyTheme · Biological productsTheme · Healthcare: biopharma and medtech· L3VLUP-defined
Quarter
Q3 2026 · early filersQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
19 Feb 2026
latest of these filings; the earliest 23 Jan 2026
Managers listing it
28
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 5 listed it in both
Shares listed
39,828,808
combined, among listed positions
Reported value
$658m
combined, at the quarter end

Among the 92 comparable managers: 15 buyers (opened or added shares) and 15 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was -2,200,718.

Managers listing DNLI in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

28 of 28 holders

ActionFiling
Baillie Gifford & Co12,310,889$203m0.17%Added+719,30423 Jan 2026 (the filing on sec.gov)
Fidelity (FMR LLC)6,097,211$101munder 0.1%Trimmed-243,10517 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc3,915,951$65munder 0.1%Trimmed-652,41717 Feb 2026 (the filing on sec.gov)
Capital Research Global Investors3,729,244$62munder 0.1%Trimmed-1,031,61411 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP3,557,935$59munder 0.1%Added+37,52117 Feb 2026 (the filing on sec.gov)
Holocene Advisors LP3,152,734$52m0.11%Added+17,02217 Feb 2026 (the filing on sec.gov)
Point72 Asset Management LP1,700,000$28munder 0.1%Trimmed-819,53517 Feb 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP1,023,253$17m0.13%Newnew17 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC779,148$13munder 0.1%Added+90,92417 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP763,892$13munder 0.1%Trimmed-23,13713 Feb 2026 (the filing on sec.gov)
Voloridge Investment Management LLC591,461$9.8munder 0.1%Trimmed-344,76917 Feb 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP450,000$7.4munder 0.1%Added+145,00013 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP430,177$7.1munder 0.1%Added+163,88517 Feb 2026 (the filing on sec.gov)
Millennium Management LLC369,767$6.1munder 0.1%Trimmed-937,40417 Feb 2026 (the filing on sec.gov)
Invesco Ltd291,936$4.8munder 0.1%Added+42,46919 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP154,800$2.6munder 0.1%Added+64,80017 Feb 2026 (the filing on sec.gov)
Woodline Partners LP114,082$1.9munder 0.1%Added+56517 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd60,028$991kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP54,543$901kunder 0.1%Trimmed-4,69117 Feb 2026 (the filing on sec.gov)
Tudor Investment Corp53,683$886kunder 0.1%Trimmed-2,68517 Feb 2026 (the filing on sec.gov)
Man Group PLC48,994$809kunder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Jane Street Group LLC42,922$709kunder 0.1%Trimmed-181,98112 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC38,438$635kunder 0.1%Added+14,29917 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP34,768$574kunder 0.1%Trimmed-6,21817 Feb 2026 (the filing on sec.gov)
Polen Capital Management LLC26,900$444kunder 0.1%Newnew12 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (5)

Exited (3)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
7 in Q3 2024 to 5 in Q2 2026

Tracked managers listing it, at least.

035810201820192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
DNLI by quarter
QuarterHoldersReported valueBuyersSellers
Q4 20172$78mn.a.n.a.
Q1 20181$102mn.a.n.a.
Q2 20181$82mn.a.n.a.
Q3 20182$122mn.a.n.a.
Q4 20182$131mn.a.n.a.
Q1 20192$146mn.a.n.a.
Q2 20192$154mn.a.n.a.
Q3 20192$113mn.a.n.a.
Q4 20192$133mn.a.n.a.
Q1 20203$165mn.a.n.a.
Q2 20202$226mn.a.n.a.
Q3 20204$406mn.a.n.a.
Q4 20207$1.6bnn.a.n.a.
Q1 20217$1.2bnn.a.n.a.
Q2 20215$1.7bnn.a.n.a.
Q3 20216$1.1bnn.a.n.a.
Q4 20214$709mn.a.n.a.
Q1 20223$507mn.a.n.a.
Q2 20225$481mn.a.n.a.
Q3 20228$629mn.a.n.a.
Q4 20226$766mn.a.n.a.
Q1 20234$423mn.a.n.a.
Q2 20236$760mn.a.n.a.
Q3 20235$539mn.a.n.a.
Q4 20238$577m44
Q1 20249$669m72
Q2 20249$829m53
Q3 20247$1.1bn44
Q4 20246$625m15
Q1 20255$422m23
Q2 20254$270m23
Q3 20255$333m41
Q4 20256$342m1515
Q1 20267$372m1316
Q2 20265$514m1312

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

DNLI and GILD →DNLI and AMGN →DNLI and ARGX →Choose a stock to compare with DNLI →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own DNLI, latest filings →Back to the 13F Explorer →