L3VLUP
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
28
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 7 listed it in both
Shares listed
4,349,199
combined, among listed positions
Reported value
$1.3bn
combined, at the quarter end

Among the 92 comparable managers: 12 buyers (opened or added shares) and 21 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +370,177.

Managers listing BIO in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

28 of 28 holders

ActionFiling
First Eagle Investment Management LLC2,570,473$779m1.37%Added+50,1544 Feb 2026 (the filing on sec.gov)
Capital Research Global Investors494,472$150munder 0.1%Added+76,11711 Feb 2026 (the filing on sec.gov)
MFS Investment Management399,207$121munder 0.1%Added+390,59322 Jan 2026 (the filing on sec.gov)
Southeastern Asset Management Inc227,630$69m3.07%Trimmed-9,62413 Feb 2026 (the filing on sec.gov)
Acadian Asset Management LLC120,634$37m0.06%Trimmed-18,25510 Feb 2026 (the filing on sec.gov)
Freestone Grove Partners LP110,524$33m0.24%Newnew17 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc76,271$23munder 0.1%Added+79417 Feb 2026 (the filing on sec.gov)
Jane Street Group LLC73,967$22munder 0.1%Added+32,21612 Feb 2026 (the filing on sec.gov)
Moore Capital Management LP50,000$15m0.22%Trimmed-5,00017 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC40,195$12munder 0.1%Added+8,22417 Feb 2026 (the filing on sec.gov)
Invesco Ltd35,060$11munder 0.1%Trimmed-87219 Feb 2026 (the filing on sec.gov)
GAMCO Investors Inc26,750$8.1m0.08%Held05 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP23,281$7.1munder 0.1%Trimmed-2,52617 Feb 2026 (the filing on sec.gov)
Millennium Management LLC22,206$6.7munder 0.1%Trimmed-2,24917 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP11,560$3.5munder 0.1%Trimmed-1,05413 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC9,480$2.9munder 0.1%Trimmed-40,82617 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP9,100$2.8munder 0.1%Trimmed-40017 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd7,900$2.4munder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Man Group PLC6,251$1.9munder 0.1%Trimmed-26,73217 Feb 2026 (the filing on sec.gov)
Quantbot Technologies LP6,102$1.8m0.06%Newnew10 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC5,425$1.6munder 0.1%Trimmed-49,31013 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.4,830$1.5munder 0.1%Added+1,53017 Feb 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP4,293$1.3munder 0.1%Trimmed-19,17917 Feb 2026 (the filing on sec.gov)
Verition Fund Management LLC3,901$1.2munder 0.1%Trimmed-2,45413 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)3,239$981kunder 0.1%Added+32317 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
9 in Q3 2024 to 7 in Q2 2026

Tracked managers listing it, at least.

01020302014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
BIO by quarter
QuarterHoldersReported valueBuyersSellers
Q2 20135$24mn.a.n.a.
Q3 20134$22mn.a.n.a.
Q4 20132$13mn.a.n.a.
Q1 20143$34mn.a.n.a.
Q2 20144$33mn.a.n.a.
Q3 20145$22mn.a.n.a.
Q4 20145$41mn.a.n.a.
Q1 20158$145mn.a.n.a.
Q2 20156$170mn.a.n.a.
Q3 20157$201mn.a.n.a.
Q4 20157$186mn.a.n.a.
Q1 20166$182mn.a.n.a.
Q2 20164$188mn.a.n.a.
Q3 20164$224mn.a.n.a.
Q4 20167$317mn.a.n.a.
Q1 20179$340mn.a.n.a.
Q2 20178$298mn.a.n.a.
Q3 20174$294mn.a.n.a.
Q4 201713$478mn.a.n.a.
Q1 201813$524mn.a.n.a.
Q2 201815$657mn.a.n.a.
Q3 201816$686mn.a.n.a.
Q4 201816$498mn.a.n.a.
Q1 201915$689mn.a.n.a.
Q2 201914$614mn.a.n.a.
Q3 201916$801mn.a.n.a.
Q4 201912$585mn.a.n.a.
Q1 202012$695mn.a.n.a.
Q2 202019$1.3bnn.a.n.a.
Q3 202017$1.7bnn.a.n.a.
Q4 202013$2.2bnn.a.n.a.
Q1 202115$2.2bnn.a.n.a.
Q2 202118$2.7bnn.a.n.a.
Q3 202116$3.5bnn.a.n.a.
Q4 202119$3.3bnn.a.n.a.
Q1 202222$2.4bnn.a.n.a.
Q2 202215$1.2bnn.a.n.a.
Q3 202217$857mn.a.n.a.
Q4 202216$782mn.a.n.a.
Q1 202311$833mn.a.n.a.
Q2 202316$607mn.a.n.a.
Q3 202315$662mn.a.n.a.
Q4 202311$534m85
Q1 20247$342m46
Q2 20246$409m32
Q3 20249$708m71
Q4 202411$649m54
Q1 202510$612m63
Q2 20258$780m43
Q3 20258$983m43
Q4 20259$1.2bn1221
Q1 20268$1.2bn1814
Q2 20267$1.1bn1513

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

BIO and LLY →BIO and JNJ →BIO and VRTX →Choose a stock to compare with BIO →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own BIO, latest filings →Back to the 13F Explorer →