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XENE in the 13F filings

Xenon Pharmaceuticals Inc · CUSIP 98420N105

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 11 Feb 2026
Managers listing it
22
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 5 listed it in both
Shares listed
25,953,273
combined, among listed positions
Reported value
$1.2bn
combined, at the quarter end

Among the 92 comparable managers: 12 buyers (opened or added shares) and 12 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +1,122,263.

Managers listing XENE in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

22 of 22 holders

ActionFiling
Fidelity (FMR LLC)8,920,250$400munder 0.1%Added+1,34317 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP4,764,779$214munder 0.1%Added+1,154,92217 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd4,084,034$183m0.08%Added+140,14917 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP1,593,814$71munder 0.1%Trimmed-60,60317 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC1,321,213$59munder 0.1%Added+362,11517 Feb 2026 (the filing on sec.gov)
Holocene Advisors LP1,282,081$57m0.12%Trimmed-694,47217 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc862,300$39munder 0.1%Added+820,60817 Feb 2026 (the filing on sec.gov)
Capital World Investors655,737$29munder 0.1%Held011 Feb 2026 (the filing on sec.gov)
Millennium Management LLC635,056$28munder 0.1%Trimmed-748,95117 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP436,743$20munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP259,320$12munder 0.1%Added+241,22017 Feb 2026 (the filing on sec.gov)
Tudor Investment Corp254,002$11munder 0.1%Added+177,17817 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC178,747$8.0munder 0.1%Added+6,39327 Oct 2026 (the filing on sec.gov)
Marshall Wace LLP162,551$7.3munder 0.1%Trimmed-449,43113 Feb 2026 (the filing on sec.gov)
Moore Capital Management LP140,000$6.3m0.09%Held017 Feb 2026 (the filing on sec.gov)
Man Group PLC114,826$5.1munder 0.1%Added+91,70717 Feb 2026 (the filing on sec.gov)
Verition Fund Management LLC93,756$4.2munder 0.1%Added+36,63913 Feb 2026 (the filing on sec.gov)
Balyasny Asset Management LLC84,360$3.8munder 0.1%Trimmed-238,09617 Feb 2026 (the filing on sec.gov)
Invesco Ltd50,947$2.3munder 0.1%Trimmed-5,11719 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.30,851$1.4munder 0.1%Trimmed-17,60417 Feb 2026 (the filing on sec.gov)
Walleye Capital LLC19,587$878kunder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP8,319$373kunder 0.1%Trimmed-37,58817 Feb 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (2)

Exited (4)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
7 in Q3 2024 to 9 in Q2 2026

Tracked managers listing it, at least.

051015201520162017201820192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
XENE by quarter
QuarterHoldersReported valueBuyersSellers
Q4 20141$12mn.a.n.a.
Q1 20151$11mn.a.n.a.
Q3 20151$8.5mn.a.n.a.
Q4 20151$8.3mn.a.n.a.
Q1 20161$7.2mn.a.n.a.
Q2 20161$6.1mn.a.n.a.
Q3 20161$8.3mn.a.n.a.
Q4 20161$9.4mn.a.n.a.
Q1 20171$5.7mn.a.n.a.
Q2 20172$4.9mn.a.n.a.
Q3 20172$5.0mn.a.n.a.
Q4 20172$5.1mn.a.n.a.
Q1 20182$8.9mn.a.n.a.
Q2 20183$17mn.a.n.a.
Q3 20185$21mn.a.n.a.
Q4 20183$9.5mn.a.n.a.
Q1 20194$24mn.a.n.a.
Q2 20193$19mn.a.n.a.
Q3 20193$17mn.a.n.a.
Q4 20193$25mn.a.n.a.
Q1 20202$18mn.a.n.a.
Q2 20203$21mn.a.n.a.
Q1 20211$14mn.a.n.a.
Q2 20211$17mn.a.n.a.
Q3 20212$20mn.a.n.a.
Q4 20214$205mn.a.n.a.
Q1 20226$215mn.a.n.a.
Q2 20227$230mn.a.n.a.
Q3 20227$330mn.a.n.a.
Q4 20228$303mn.a.n.a.
Q1 20239$259mn.a.n.a.
Q2 20235$222mn.a.n.a.
Q3 20237$220mn.a.n.a.
Q4 202311$590m83
Q1 20246$396m05
Q2 20247$383m32
Q3 20247$428m32
Q4 20246$400m23
Q1 20255$343m22
Q2 20255$224m41
Q3 20255$415m40
Q4 20256$501m1212
Q1 20268$1.3bn229
Q2 20269$1.2bn1715

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

XENE and LLY →XENE and JNJ →XENE and VRTX →Choose a stock to compare with XENE →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own XENE, latest filings →Back to the 13F Explorer →