L3VLUP
Quarter end
31 Mar 2025
the date the book describes
Filed
5 Nov 2026
latest of these filings; the earliest 2 May 2025
Managers listing it
21
at least, of 95 tracked, among listed positions
Comparable managers
95
filed both Q4 2024 and Q1 2025; 19 listed it in both
Shares listed
73,045,318
combined, among listed positions
Reported value
$35.4bn
combined, at the quarter end

Among the 95 comparable managers: 10 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares is not known from listed positions, because at least one of them lists it in only one of the two quarters.

Managers listing VRTX in Q1 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2024, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

21 of 21 holders

ActionFiling
Capital World Investors28,533,308$13.8bn2.24%Added+207,61312 May 2025 (the filing on sec.gov)
Capital Research Global Investors14,536,344$7.0bn1.53%Added+4,107,39312 May 2025 (the filing on sec.gov)
Fidelity (FMR LLC)7,727,184$3.7bn0.24%Trimmed-1,491,8625 Nov 2026 (the filing on sec.gov)
Wellington Management Group LLP5,454,748$2.6bn0.51%Trimmed-461,33613 May 2025 (the filing on sec.gov)
AllianceBernstein LP3,953,512$1.9bn0.69%Added+33,49215 May 2025 (the filing on sec.gov)
T. Rowe Price Associates Inc2,917,227$1.4bn0.17%Added+1,226,52714 May 2025 (the filing on sec.gov)
Janus Henderson Group Ltd2,747,937$1.4bn0.74%Trimmed-85,95215 May 2025 (the filing on sec.gov)
MFS Investment Management2,024,908$982m0.33%Trimmed-263,5902 May 2025 (the filing on sec.gov)
Invesco Ltd1,845,640$895m0.17%Trimmed-52,81712 May 2025 (the filing on sec.gov)
Renaissance Technologies LLC1,171,571$568m0.86%Trimmed-225,63814 May 2025 (the filing on sec.gov)
Artisan Partners LP719,131$349m0.56%Added+54,60814 May 2025 (the filing on sec.gov)
Neuberger Berman Group LLC442,628$215m0.18%Added+8,31727 Oct 2026 (the filing on sec.gov)
Millennium Management LLC309,935$150m0.08%Trimmed-70815 May 2025 (the filing on sec.gov)
Woodline Partners LP153,160$74m0.48%Added+3,74215 May 2025 (the filing on sec.gov)
AQR Capital Management LLC145,871$70m0.07%Trimmed-99,91415 May 2025 (the filing on sec.gov)
Marshall Wace LLP138,000$67m0.08%Trimmed-56,00015 May 2025 (the filing on sec.gov)
Baillie Gifford & Co134,465$65m0.06%Trimmed-15,3737 May 2025 (the filing on sec.gov)
Hudson Bay Capital Management LP49,841$24m0.07%Addedn.a.14 May 2025 (the filing on sec.gov)
ARK Investment Management LLC26,344$13m0.13%Added+9947 May 2025 (the filing on sec.gov)
PDT Partners LLC8,116$3.9m0.28%Trimmed-1,68715 May 2025 (the filing on sec.gov)
Element Capital Management LLC5,448$2.6m0.66%Newnew13 May 2025 (the filing on sec.gov)

Largest increases and reductions, by shares

Q4 2024 to Q1 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Exited (0)

No exit shown by a manager’s own filing.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
27 in Q3 2024 to 26 in Q2 2026

Tracked managers listing it, at least.

0102030402014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
VRTX by quarter
QuarterHoldersReported valueBuyersSellers
Q2 201313$5.0bnn.a.n.a.
Q3 201312$4.6bnn.a.n.a.
Q4 20139$4.8bnn.a.n.a.
Q1 201411$4.9bnn.a.n.a.
Q2 201411$7.3bnn.a.n.a.
Q3 201414$9.0bnn.a.n.a.
Q4 201415$9.3bnn.a.n.a.
Q1 201521$9.2bnn.a.n.a.
Q2 201523$9.4bnn.a.n.a.
Q3 201522$8.3bnn.a.n.a.
Q4 201519$10.2bnn.a.n.a.
Q1 201618$6.8bnn.a.n.a.
Q2 201613$7.5bnn.a.n.a.
Q3 201614$7.7bnn.a.n.a.
Q4 201614$6.3bnn.a.n.a.
Q1 201721$9.5bnn.a.n.a.
Q2 201724$11.0bnn.a.n.a.
Q3 201728$12.6bnn.a.n.a.
Q4 201724$12.2bnn.a.n.a.
Q1 201824$13.3bnn.a.n.a.
Q2 201827$14.0bnn.a.n.a.
Q3 201826$15.7bnn.a.n.a.
Q4 201827$14.6bnn.a.n.a.
Q1 201926$17.0bnn.a.n.a.
Q2 201924$17.0bnn.a.n.a.
Q3 201925$16.0bnn.a.n.a.
Q4 201929$20.0bnn.a.n.a.
Q1 202027$20.9bnn.a.n.a.
Q2 202027$23.4bnn.a.n.a.
Q3 202031$21.9bnn.a.n.a.
Q4 202030$18.4bnn.a.n.a.
Q1 202131$15.4bnn.a.n.a.
Q2 202130$12.7bnn.a.n.a.
Q3 202135$10.1bnn.a.n.a.
Q4 202128$12.4bnn.a.n.a.
Q1 202223$16.1bnn.a.n.a.
Q2 202225$18.1bnn.a.n.a.
Q3 202222$18.4bnn.a.n.a.
Q4 202228$18.4bnn.a.n.a.
Q1 202326$21.4bnn.a.n.a.
Q2 202327$24.7bnn.a.n.a.
Q3 202333$24.3bnn.a.n.a.
Q4 202332$28.6bn1616
Q1 202431$29.8bn1619
Q2 202429$33.4bn1218
Q3 202427$33.5bn1710
Q4 202426$28.5bn1413
Q1 202521$35.4bn1011
Q2 202521$32.3bn1111
Q3 202522$25.9bn1310
Q4 202526$31.8bn1920
Q1 202625$31.8bn1721
Q2 202626$34.6bn2117

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

VRTX and LLY →VRTX and JNJ →VRTX and GILD →Choose a stock to compare with VRTX →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own VRTX, latest filings →Back to the 13F Explorer →