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VRTX in the 13F filings

Vertex Pharmaceuticals Inc · CUSIP 92532F100

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q3 2026 · early filersQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
35
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 20 listed it in both
Shares listed
70,400,273
combined, among listed positions
Reported value
$31.9bn
combined, at the quarter end

Among the 92 comparable managers: 19 buyers (opened or added shares) and 20 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +3,451,758.

Managers listing VRTX in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

35 of 35 holders

ActionFiling
Capital World Investors25,510,182$11.6bn1.57%Trimmed-400,40511 Feb 2026 (the filing on sec.gov)
Capital Research Global Investors17,316,344$7.9bn1.45%Added+763,06311 Feb 2026 (the filing on sec.gov)
Invesco Ltd7,852,733$3.6bn0.34%Added+5,755,93619 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP4,496,482$2.0bn0.64%Trimmed-26,10417 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP3,821,731$1.7bn0.30%Trimmed-950,31117 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc2,278,958$1.0bn0.11%Trimmed-764,84717 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd2,221,953$1.0bn0.45%Added+102,84617 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)2,212,596$1.0bn0.05%Trimmed-1,091,17217 Feb 2026 (the filing on sec.gov)
Arrowstreet Capital LP593,947$269m0.16%Added+212,75213 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC545,897$247m0.18%Added+18,40627 Oct 2026 (the filing on sec.gov)
Renaissance Technologies LLC505,048$229m0.36%Trimmed-230,84012 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC427,060$194munder 0.1%Added+253,55817 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC389,020$176m0.19%Trimmed-218,81613 Feb 2026 (the filing on sec.gov)
Man Group PLC380,735$173m0.29%Added+17,96117 Feb 2026 (the filing on sec.gov)
Millennium Management LLC365,664$166m0.07%Added+324,62217 Feb 2026 (the filing on sec.gov)
MFS Investment Management211,934$96munder 0.1%Trimmed-291,22622 Jan 2026 (the filing on sec.gov)
Marshall Wace LLP204,032$93m0.08%Added+158,14713 Feb 2026 (the filing on sec.gov)
Baillie Gifford & Co201,088$91m0.08%Trimmed-5,96823 Jan 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP164,518$75m0.25%Added+119,20313 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC143,651$65munder 0.1%Trimmed-18,03217 Feb 2026 (the filing on sec.gov)
Woodline Partners LP127,726$58m0.22%Trimmed-25,54617 Feb 2026 (the filing on sec.gov)
Balyasny Asset Management LLC113,488$51m0.07%Newnew17 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP98,360$45m0.09%Added+86,86017 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP84,096$38munder 0.1%Added+16,41317 Feb 2026 (the filing on sec.gov)
Bridgewater Associates LP27,488$12munder 0.1%Trimmed-10,83613 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (4)

Exited (4)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
27 in Q3 2024 to 26 in Q2 2026

Tracked managers listing it, at least.

0102030402014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
VRTX by quarter
QuarterHoldersReported valueBuyersSellers
Q2 201313$5.0bnn.a.n.a.
Q3 201312$4.6bnn.a.n.a.
Q4 20139$4.8bnn.a.n.a.
Q1 201411$4.9bnn.a.n.a.
Q2 201411$7.3bnn.a.n.a.
Q3 201414$9.0bnn.a.n.a.
Q4 201415$9.3bnn.a.n.a.
Q1 201521$9.2bnn.a.n.a.
Q2 201523$9.4bnn.a.n.a.
Q3 201522$8.3bnn.a.n.a.
Q4 201519$10.2bnn.a.n.a.
Q1 201618$6.8bnn.a.n.a.
Q2 201613$7.5bnn.a.n.a.
Q3 201614$7.7bnn.a.n.a.
Q4 201614$6.3bnn.a.n.a.
Q1 201721$9.5bnn.a.n.a.
Q2 201724$11.0bnn.a.n.a.
Q3 201728$12.6bnn.a.n.a.
Q4 201724$12.2bnn.a.n.a.
Q1 201824$13.3bnn.a.n.a.
Q2 201827$14.0bnn.a.n.a.
Q3 201826$15.7bnn.a.n.a.
Q4 201827$14.6bnn.a.n.a.
Q1 201926$17.0bnn.a.n.a.
Q2 201924$17.0bnn.a.n.a.
Q3 201925$16.0bnn.a.n.a.
Q4 201929$20.0bnn.a.n.a.
Q1 202027$20.9bnn.a.n.a.
Q2 202027$23.4bnn.a.n.a.
Q3 202031$21.9bnn.a.n.a.
Q4 202030$18.4bnn.a.n.a.
Q1 202131$15.4bnn.a.n.a.
Q2 202130$12.7bnn.a.n.a.
Q3 202135$10.1bnn.a.n.a.
Q4 202128$12.4bnn.a.n.a.
Q1 202223$16.1bnn.a.n.a.
Q2 202225$18.1bnn.a.n.a.
Q3 202222$18.4bnn.a.n.a.
Q4 202228$18.4bnn.a.n.a.
Q1 202326$21.4bnn.a.n.a.
Q2 202327$24.7bnn.a.n.a.
Q3 202333$24.3bnn.a.n.a.
Q4 202332$28.6bn1616
Q1 202431$29.8bn1619
Q2 202429$33.4bn1218
Q3 202427$33.5bn1710
Q4 202426$28.5bn1413
Q1 202521$35.4bn1011
Q2 202521$32.3bn1111
Q3 202522$25.9bn1310
Q4 202526$31.8bn1920
Q1 202625$31.8bn1721
Q2 202626$34.6bn2117

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

VRTX and LLY →VRTX and JNJ →VRTX and GILD →Choose a stock to compare with VRTX →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own VRTX, latest filings →Back to the 13F Explorer →