L3VLUP
Quarter end
31 Mar 2026
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 8 May 2026
Managers listing it
35
at least, of 95 tracked, among listed positions
Comparable managers
91
filed both Q4 2025 and Q1 2026; 23 listed it in both
Shares listed
71,854,331
combined, among listed positions
Reported value
$32.1bn
combined, at the quarter end

AllianceBernstein LP. Values in this filing are at the previous quarter end's prices; its share count is the quarter end's.

Among the 91 comparable managers: 17 buyers (opened or added shares) and 21 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +1,552,418.

Managers listing VRTX in Q1 2026

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

35 of 35 holders

ActionFiling
Capital World Investors25,368,124$11.3bn1.55%Trimmed-142,05813 May 2026 (the filing on sec.gov)
Capital Research Global Investors21,125,964$9.4bn1.46%Added+3,809,62013 May 2026 (the filing on sec.gov)
Invesco Ltd7,892,611$3.5bn0.34%Added+39,87812 May 2026 (the filing on sec.gov)
AllianceBernstein LP3,910,786$1.8bn0.57%Trimmed-585,69615 May 2026 (the filing on sec.gov)
Wellington Management Group LLP3,212,589$1.4bn0.27%Trimmed-609,14215 May 2026 (the filing on sec.gov)
Janus Henderson Group Ltd2,131,527$952m0.45%Trimmed-90,42618 May 2026 (the filing on sec.gov)
Fidelity (FMR LLC)2,020,265$902munder 0.1%Trimmed-192,33115 May 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc1,760,122$786m0.09%Trimmed-518,83615 May 2026 (the filing on sec.gov)
Arrowstreet Capital LP638,950$285m0.15%Added+45,00314 May 2026 (the filing on sec.gov)
Neuberger Berman Group LLC551,522$246m0.19%Added+5,62527 Oct 2026 (the filing on sec.gov)
Renaissance Technologies LLC421,688$188m0.29%Trimmed-83,36014 May 2026 (the filing on sec.gov)
Two Sigma Investments LP378,146$169m0.14%Added+373,99115 May 2026 (the filing on sec.gov)
Citadel Advisors LLC339,298$152munder 0.1%Trimmed-87,76215 May 2026 (the filing on sec.gov)
MFS Investment Management327,498$149m0.05%Added+115,56414 May 2026 (the filing on sec.gov)
Marshall Wace LLP317,058$142m0.14%Added+113,02615 May 2026 (the filing on sec.gov)
D. E. Shaw & Co.248,960$111m0.07%Newnew15 May 2026 (the filing on sec.gov)
Man Group PLC236,798$106m0.19%Trimmed-143,93715 May 2026 (the filing on sec.gov)
Baillie Gifford & Co199,421$89m0.09%Trimmed-1,6678 May 2026 (the filing on sec.gov)
AQR Capital Management LLC171,031$76munder 0.1%Added+27,38015 May 2026 (the filing on sec.gov)
Woodline Partners LP134,954$60m0.23%Added+7,22815 May 2026 (the filing on sec.gov)
Jane Street Group LLC122,946$55munder 0.1%Added+111,70012 May 2026 (the filing on sec.gov)
Holocene Advisors LP67,618$30m0.07%Added+66,14015 May 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP45,000$20m0.07%Trimmed-119,51813 May 2026 (the filing on sec.gov)
Balyasny Asset Management LLC40,137$18munder 0.1%Trimmed-73,35115 May 2026 (the filing on sec.gov)
Caxton Associates LLP36,026$16m0.36%Newnew14 May 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q4 2025 to Q1 2026, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
27 in Q3 2024 to 26 in Q2 2026

Tracked managers listing it, at least.

0102030402014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
VRTX by quarter
QuarterHoldersReported valueBuyersSellers
Q2 201313$5.0bnn.a.n.a.
Q3 201312$4.6bnn.a.n.a.
Q4 20139$4.8bnn.a.n.a.
Q1 201411$4.9bnn.a.n.a.
Q2 201411$7.3bnn.a.n.a.
Q3 201414$9.0bnn.a.n.a.
Q4 201415$9.3bnn.a.n.a.
Q1 201521$9.2bnn.a.n.a.
Q2 201523$9.4bnn.a.n.a.
Q3 201522$8.3bnn.a.n.a.
Q4 201519$10.2bnn.a.n.a.
Q1 201618$6.8bnn.a.n.a.
Q2 201613$7.5bnn.a.n.a.
Q3 201614$7.7bnn.a.n.a.
Q4 201614$6.3bnn.a.n.a.
Q1 201721$9.5bnn.a.n.a.
Q2 201724$11.0bnn.a.n.a.
Q3 201728$12.6bnn.a.n.a.
Q4 201724$12.2bnn.a.n.a.
Q1 201824$13.3bnn.a.n.a.
Q2 201827$14.0bnn.a.n.a.
Q3 201826$15.7bnn.a.n.a.
Q4 201827$14.6bnn.a.n.a.
Q1 201926$17.0bnn.a.n.a.
Q2 201924$17.0bnn.a.n.a.
Q3 201925$16.0bnn.a.n.a.
Q4 201929$20.0bnn.a.n.a.
Q1 202027$20.9bnn.a.n.a.
Q2 202027$23.4bnn.a.n.a.
Q3 202031$21.9bnn.a.n.a.
Q4 202030$18.4bnn.a.n.a.
Q1 202131$15.4bnn.a.n.a.
Q2 202130$12.7bnn.a.n.a.
Q3 202135$10.1bnn.a.n.a.
Q4 202128$12.4bnn.a.n.a.
Q1 202223$16.1bnn.a.n.a.
Q2 202225$18.1bnn.a.n.a.
Q3 202222$18.4bnn.a.n.a.
Q4 202228$18.4bnn.a.n.a.
Q1 202326$21.4bnn.a.n.a.
Q2 202327$24.7bnn.a.n.a.
Q3 202333$24.3bnn.a.n.a.
Q4 202332$28.6bn1616
Q1 202431$29.8bn1619
Q2 202429$33.4bn1218
Q3 202427$33.5bn1710
Q4 202426$28.5bn1413
Q1 202521$35.4bn1011
Q2 202521$32.3bn1111
Q3 202522$25.9bn1310
Q4 202526$31.8bn1920
Q1 202625$31.8bn1721
Q2 202626$34.6bn2117

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

VRTX and LLY →VRTX and JNJ →VRTX and GILD →Choose a stock to compare with VRTX →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own VRTX, latest filings →Back to the 13F Explorer →