L3VLUP
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
25
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 11 listed it in both
Shares listed
16,592,439
combined, among listed positions
Reported value
$2.7bn
combined, at the quarter end

Among the 92 comparable managers: 11 buyers (opened or added shares) and 23 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +156,285.

Managers listing RGEN in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

25 of 25 holders

ActionFiling
T. Rowe Price Associates Inc4,599,061$754m0.08%Added+1,091,68317 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)2,867,846$470munder 0.1%Added+176,63417 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC1,394,252$228munder 0.1%Trimmed-290,46817 Feb 2026 (the filing on sec.gov)
Invesco Ltd1,256,439$206munder 0.1%Added+383,39919 Feb 2026 (the filing on sec.gov)
MFS Investment Management1,215,527$199m0.06%Newnew22 Jan 2026 (the filing on sec.gov)
Point72 Asset Management LP1,006,310$165m0.18%Trimmed-434,41117 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP994,869$163m0.05%Trimmed-109,30217 Feb 2026 (the filing on sec.gov)
Holocene Advisors LP961,040$157m0.33%Trimmed-416,06417 Feb 2026 (the filing on sec.gov)
Millennium Management LLC650,546$107munder 0.1%Trimmed-166,51017 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP516,336$85m0.08%Added+335,27313 Feb 2026 (the filing on sec.gov)
Walleye Capital LLC417,110$68m0.21%Added+231,35313 Feb 2026 (the filing on sec.gov)
Artisan Partners LP193,697$32munder 0.1%Trimmed-19,04417 Feb 2026 (the filing on sec.gov)
Moore Capital Management LP150,000$25m0.35%Added+5,00017 Feb 2026 (the filing on sec.gov)
Balyasny Asset Management LLC115,053$19munder 0.1%Trimmed-652,18617 Feb 2026 (the filing on sec.gov)
Woodline Partners LP46,260$7.6munder 0.1%Trimmed-59,18917 Feb 2026 (the filing on sec.gov)
Steadfast Capital Management LP45,300$7.4m0.13%Newnew17 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC42,391$6.9munder 0.1%Added+38,34227 Oct 2026 (the filing on sec.gov)
Jane Street Group LLC36,816$6.0munder 0.1%Trimmed-108,40012 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd24,316$4.0munder 0.1%Added+1,50017 Feb 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP20,000$3.3munder 0.1%Trimmed-1,00313 Feb 2026 (the filing on sec.gov)
Brevan Howard Capital Management LP11,409$1.9munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC8,648$1.4munder 0.1%Trimmed-56817 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP8,400$1.4munder 0.1%Trimmed-86,46117 Feb 2026 (the filing on sec.gov)
Bridgewater Associates LP7,874$1.3munder 0.1%Trimmed-25,74213 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP2,939$482kunder 0.1%Trimmed-34,40617 Feb 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
10 in Q3 2024 to 10 in Q2 2026

Tracked managers listing it, at least.

051015201420182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
RGEN by quarter
QuarterHoldersReported valueBuyersSellers
Q3 20131$14mn.a.n.a.
Q4 20131$18mn.a.n.a.
Q1 20141$17mn.a.n.a.
Q2 20142$33mn.a.n.a.
Q3 20142$28mn.a.n.a.
Q4 20142$24mn.a.n.a.
Q1 20153$47mn.a.n.a.
Q2 20152$41mn.a.n.a.
Q3 20152$27mn.a.n.a.
Q4 20152$23mn.a.n.a.
Q2 20162$32mn.a.n.a.
Q3 20163$45mn.a.n.a.
Q4 20163$13mn.a.n.a.
Q1 20172$2.8mn.a.n.a.
Q2 20173$7.7mn.a.n.a.
Q3 20171$1.5mn.a.n.a.
Q4 20171$2.3mn.a.n.a.
Q1 20182$2.0mn.a.n.a.
Q2 20182$3.3mn.a.n.a.
Q3 20183$149mn.a.n.a.
Q4 20185$121mn.a.n.a.
Q1 20195$262mn.a.n.a.
Q2 20195$498mn.a.n.a.
Q3 20194$419mn.a.n.a.
Q4 20194$443mn.a.n.a.
Q1 202012$838mn.a.n.a.
Q2 202013$1.1bnn.a.n.a.
Q3 202011$1.1bnn.a.n.a.
Q4 202011$1.6bnn.a.n.a.
Q1 202113$1.4bnn.a.n.a.
Q2 202113$1.5bnn.a.n.a.
Q3 202112$2.0bnn.a.n.a.
Q4 202114$1.9bnn.a.n.a.
Q1 202210$1.5bnn.a.n.a.
Q2 20228$1.8bnn.a.n.a.
Q3 20229$1.7bnn.a.n.a.
Q4 20229$1.7bnn.a.n.a.
Q1 20238$1.6bnn.a.n.a.
Q2 20236$1.1bnn.a.n.a.
Q3 20237$1.6bnn.a.n.a.
Q4 20238$1.6bn44
Q1 20248$1.5bn54
Q2 202410$959m74
Q3 202410$1.3bn74
Q4 202411$1.7bn92
Q1 202511$1.7bn75
Q2 202510$1.5bn55
Q3 202513$1.5bn95
Q4 202512$2.0bn1123
Q1 20269$1.2bn1116
Q2 202610$1.2bn1910

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

RGEN and GILD →RGEN and AMGN →RGEN and ARGX →Choose a stock to compare with RGEN →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own RGEN, latest filings →Back to the 13F Explorer →