L3VLUP
Quarter end
31 Mar 2026
the date the book describes
Filed
18 May 2026
latest of these filings; the earliest 12 May 2026
Managers listing it
29
at least, of 95 tracked, among listed positions
Comparable managers
91
filed both Q4 2025 and Q1 2026; 5 listed it in both
Shares listed
22,302,433
combined, among listed positions
Reported value
$467m
combined, at the quarter end

AllianceBernstein LP. Values in this filing are at the previous quarter end's prices; its share count is the quarter end's.

Among the 91 comparable managers: 18 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +4,567,353.

Managers listing RARE in Q1 2026

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

29 of 29 holders

ActionFiling
AQR Capital Management LLC4,578,024$96munder 0.1%Added+3,217,52715 May 2026 (the filing on sec.gov)
Wellington Management Group LLP2,640,812$55munder 0.1%Added+178,90215 May 2026 (the filing on sec.gov)
Two Sigma Investments LP2,205,820$46munder 0.1%Added+1,781,77115 May 2026 (the filing on sec.gov)
Citadel Advisors LLC2,115,491$44munder 0.1%Trimmed-210,63415 May 2026 (the filing on sec.gov)
Millennium Management LLC1,772,184$37munder 0.1%Added+891,54015 May 2026 (the filing on sec.gov)
Voloridge Investment Management LLC1,426,834$30m0.12%Added+783,47815 May 2026 (the filing on sec.gov)
D. E. Shaw & Co.1,261,018$26munder 0.1%Added+916,25515 May 2026 (the filing on sec.gov)
Point72 Asset Management LP893,295$19munder 0.1%Newnew15 May 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc804,109$17munder 0.1%Trimmed-750,25715 May 2026 (the filing on sec.gov)
Renaissance Technologies LLC561,700$12munder 0.1%Added+195,60014 May 2026 (the filing on sec.gov)
Susquehanna International Group LLP524,798$11munder 0.1%Added+372,48215 May 2026 (the filing on sec.gov)
Schonfeld Strategic Advisors LLC494,737$10m0.07%Trimmed-246,88115 May 2026 (the filing on sec.gov)
Squarepoint Ops LLC444,539$9.3munder 0.1%Added+53,94015 May 2026 (the filing on sec.gov)
Balyasny Asset Management LLC384,364$8.1munder 0.1%Trimmed-135,69015 May 2026 (the filing on sec.gov)
Invesco Ltd289,572$6.1munder 0.1%Added+59,30112 May 2026 (the filing on sec.gov)
Fidelity (FMR LLC)287,316$6.0munder 0.1%Trimmed-2,378,93315 May 2026 (the filing on sec.gov)
MFS Investment Management260,385$5.5munder 0.1%Trimmed-49,72314 May 2026 (the filing on sec.gov)
Brevan Howard Capital Management LP215,845$4.5munder 0.1%Added+107,94215 May 2026 (the filing on sec.gov)
Man Group PLC213,352$4.5munder 0.1%Added+134,98115 May 2026 (the filing on sec.gov)
Jane Street Group LLC173,743$3.6munder 0.1%Trimmed-847,75612 May 2026 (the filing on sec.gov)
Woodline Partners LP171,805$3.6munder 0.1%Held015 May 2026 (the filing on sec.gov)
Marshall Wace LLP157,526$3.3munder 0.1%Added+85,35815 May 2026 (the filing on sec.gov)
Moore Capital Management LP157,132$3.3m0.07%Trimmed-42,86815 May 2026 (the filing on sec.gov)
Walleye Capital LLC119,705$2.5munder 0.1%Added+83,22113 May 2026 (the filing on sec.gov)
Tudor Investment Corp53,517$1.1munder 0.1%Added+40,10115 May 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q4 2025 to Q1 2026, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
16 in Q3 2024 to 7 in Q2 2026

Tracked managers listing it, at least.

051015202014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
RARE by quarter
QuarterHoldersReported valueBuyersSellers
Q1 20142$108mn.a.n.a.
Q2 20142$103mn.a.n.a.
Q3 20142$237mn.a.n.a.
Q4 20142$187mn.a.n.a.
Q1 20156$676mn.a.n.a.
Q2 20157$1.2bnn.a.n.a.
Q3 20159$1.3bnn.a.n.a.
Q4 20159$1.7bnn.a.n.a.
Q1 20163$933mn.a.n.a.
Q2 20164$461mn.a.n.a.
Q3 20166$1.1bnn.a.n.a.
Q4 20165$1.2bnn.a.n.a.
Q1 20175$1.1bnn.a.n.a.
Q2 20173$661mn.a.n.a.
Q3 20173$505mn.a.n.a.
Q4 20175$532mn.a.n.a.
Q1 20186$655mn.a.n.a.
Q2 20186$1.3bnn.a.n.a.
Q3 20186$1.3bnn.a.n.a.
Q4 20186$598mn.a.n.a.
Q1 20197$1.3bnn.a.n.a.
Q2 20197$1.3bnn.a.n.a.
Q3 20196$767mn.a.n.a.
Q4 20196$685mn.a.n.a.
Q1 20206$791mn.a.n.a.
Q2 20205$1.5bnn.a.n.a.
Q3 20206$1.6bnn.a.n.a.
Q4 20208$3.0bnn.a.n.a.
Q1 202110$2.6bnn.a.n.a.
Q2 202114$2.3bnn.a.n.a.
Q3 20219$2.0bnn.a.n.a.
Q4 20218$1.6bnn.a.n.a.
Q1 20228$1.5bnn.a.n.a.
Q2 20228$1.1bnn.a.n.a.
Q3 20226$487mn.a.n.a.
Q4 20228$604mn.a.n.a.
Q1 20239$502mn.a.n.a.
Q2 202311$619mn.a.n.a.
Q3 20238$397mn.a.n.a.
Q4 20239$593m72
Q1 202412$513m73
Q2 202413$413m102
Q3 202416$809m96
Q4 202411$243m74
Q1 20258$158m53
Q2 20257$120m43
Q3 20258$94m33
Q4 20255$43m1717
Q1 20265$48m1811
Q2 20267$396m1117

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

RARE and LLY →RARE and JNJ →RARE and VRTX →Choose a stock to compare with RARE →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own RARE, latest filings →Back to the 13F Explorer →