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PRAX in the 13F filings

Praxis Precision Medicines I · CUSIP 74006W207

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
22
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 3 listed it in both
Shares listed
6,595,644
combined, among listed positions
Reported value
$1.9bn
combined, at the quarter end

Among the 92 comparable managers: 18 buyers (opened or added shares) and 6 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +578,820.

Managers listing PRAX in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

22 of 22 holders

ActionFiling
Janus Henderson Group Ltd3,240,086$955m0.43%Added+476,22717 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)1,358,675$400munder 0.1%Added+1,315,46417 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc785,987$232munder 0.1%Trimmed-217,50317 Feb 2026 (the filing on sec.gov)
Point72 Asset Management LP492,346$145m0.16%Trimmed-1,003,64017 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP176,562$52munder 0.1%Added+115,32117 Feb 2026 (the filing on sec.gov)
Woodline Partners LP105,412$31m0.12%Trimmed-312,25717 Feb 2026 (the filing on sec.gov)
Invesco Ltd77,088$23munder 0.1%Added+56,22019 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP69,242$20munder 0.1%Added+1,10113 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC66,230$20munder 0.1%Newnew12 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.37,481$11munder 0.1%Added+17,68517 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC34,917$10munder 0.1%Added+27,11917 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC28,828$8.5munder 0.1%Added+6,92417 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC25,678$7.6munder 0.1%Newnew27 Oct 2026 (the filing on sec.gov)
AllianceBernstein LP25,070$7.4munder 0.1%Added+7,01017 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP23,098$6.8munder 0.1%Added+17,59017 Feb 2026 (the filing on sec.gov)
Man Group PLC21,170$6.2munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Tudor Investment Corp16,009$4.7munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Walleye Capital LLC3,587$1.1munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
MFS Investment Management3,316$977kunder 0.1%Newnew22 Jan 2026 (the filing on sec.gov)
Susquehanna International Group LLP2,343$691kunder 0.1%Trimmed-26,99417 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC1,890$557kunder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Acadian Asset Management LLC629$184kunder 0.1%Newnew10 Feb 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (8)

Exited (2)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
4 in Q3 2024 to 6 in Q2 2026

Tracked managers listing it, at least.

02468Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
PRAX by quarter
QuarterHoldersReported valueBuyersSellers
Q4 20231$16m10
Q1 20247$108m52
Q2 20242$74m22
Q3 20244$179m22
Q4 20244$224m13
Q1 20253$97m21
Q2 20252$147m21
Q3 20253$248m30
Q4 20254$1.4bn186
Q1 20266$2.1bn1512
Q2 20266$2.4bn178

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

PRAX and LLY →PRAX and JNJ →PRAX and VRTX →Choose a stock to compare with PRAX →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own PRAX, latest filings →Back to the 13F Explorer →