ORKA in the 13F filings

Oruka Therapeutics Inc · CUSIP 687604108

Sector · Pharmaceuticals and biotechnology Theme · Healthcare: biopharma and medtech· L3VLUP-defined Theme · Pharmaceutical preparations

Quarter

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q4 2024 Q3 2024

Quarter end: 31 Mar 2026; the date the book describes
Filed: 18 May 2026; latest of these filings; the earliest 12 May 2026
Managers listing it: 15; at least, of 95 tracked, among listed positions
Comparable managers: 91; filed both Q4 2025 and Q1 2026; 2 listed it in both
Shares listed: 13,034,613; combined, among listed positions
Reported value: $639m; combined, at the quarter end

AllianceBernstein LP. Values in this filing are at the previous quarter end's prices; its share count is the quarter end's.

Among the 91 comparable managers: 10 buyers (opened or added shares) and 10 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +13,083.

Managers listing ORKA in Q1 2026

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

ActionShare of book at least

15 of 15 holders

				Action		Filing
Fidelity (FMR LLC)	7,431,403	$365m	under 0.1%	Added	+170,019	15 May 2026 (the filing on sec.gov)
Viking Global Investors LP	2,666,690	$131m	0.37%	Held	0	15 May 2026 (the filing on sec.gov)
Citadel Advisors LLC	1,007,537	$49m	under 0.1%	Added	+281,419	15 May 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc	727,449	$36m	under 0.1%	Added	+78,103	15 May 2026 (the filing on sec.gov)
Woodline Partners LP	574,882	$28m	0.11%	Added	+329	15 May 2026 (the filing on sec.gov)
Holocene Advisors LP	185,513	$9.1m	under 0.1%	New	new	15 May 2026 (the filing on sec.gov)
Wellington Management Group LLP	121,225	$5.9m	under 0.1%	Added	+36,509	15 May 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP	101,354	$5.0m	under 0.1%	New	new	14 May 2026 (the filing on sec.gov)
Invesco Ltd	97,042	$4.8m	under 0.1%	Trimmed	-46,079	12 May 2026 (the filing on sec.gov)
AllianceBernstein LP	40,400	$1.2m	under 0.1%	Added	+2,600	15 May 2026 (the filing on sec.gov)
Squarepoint Ops LLC	24,463	$1.2m	under 0.1%	Trimmed	-3,208	15 May 2026 (the filing on sec.gov)
Susquehanna International Group LLP	20,984	$1.0m	under 0.1%	Added	+12,319	15 May 2026 (the filing on sec.gov)
Two Sigma Investments LP	19,364	$950k	under 0.1%	Trimmed	-9,202	15 May 2026 (the filing on sec.gov)
Janus Henderson Group Ltd	12,100	$594k	under 0.1%	Held	0	18 May 2026 (the filing on sec.gov)
AQR Capital Management LLC	4,207	$206k	under 0.1%	New	new	15 May 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q4 2025 to Q1 2026, among managers that listed it in both quarters or opened it.

Increases

Citadel Advisors LLCexisting position · 1,007,537 shares now+281,419
Holocene Advisors LPnew position · 185,513 shares now+185,513
Fidelity (FMR LLC)existing position · 7,431,403 shares now+170,019
ExodusPoint Capital Management LPnew position · 101,354 shares now+101,354
T. Rowe Price Associates Incexisting position · 727,449 shares now+78,103

Reductions

Invesco Ltdexisting position · 97,042 shares now-46,079
Two Sigma Investments LPexisting position · 19,364 shares now-9,202
Squarepoint Ops LLCexisting position · 24,463 shares now-3,208

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (3)

Exited (7)

Point72 Asset Management LPwas $18m
D. E. Shaw & Co.was $2.3m
Millennium Management LLCwas $1.8m
Verition Fund Management LLCwas $1.1m
Hudson Bay Capital Management LPwas $606k
Brevan Howard Capital Management LPwas $285k
Balyasny Asset Management LLCwas $16k

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.

1 in Q3 2024 to 8 in Q2 2026

Tracked managers listing it, at least.

the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

ORKA and LLY →ORKA and JNJ →ORKA and VRTX →Choose a stock to compare with ORKA →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own ORKA, latest filings →Back to the 13F Explorer →

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Quarter	Holders	Reported value	Buyers	Sellers
Q3 2024	1	$9.6m	1	0
Q4 2024	1	$7.6m	1	0
Q3 2025	2	$62m	2	0
Q4 2025	2	$98m	14	3
Q1 2026	4	$173m	10	10
Q2 2026	8	$1.5bn	17	6