L3VLUP
Quarter end
31 Dec 2025
the date the book describes
Filed
19 Feb 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
29
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 5 listed it in both
Shares listed
34,232,943
combined, among listed positions
Reported value
$308m
combined, at the quarter end

Among the 92 comparable managers: 21 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +6,637,428.

Managers listing NTLA in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

29 of 29 holders

ActionFiling
ARK Investment Management LLC14,207,324$128m0.85%Added+2,288,14611 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.5,331,064$48munder 0.1%Added+3,102,66417 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP2,698,738$24munder 0.1%Added+249,13117 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP2,346,317$21munder 0.1%Added+182,90017 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)1,759,898$16munder 0.1%Trimmed-92,39417 Feb 2026 (the filing on sec.gov)
Voloridge Investment Management LLC1,737,450$16m0.05%Added+127,24517 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC1,672,700$15munder 0.1%Added+1,021,70012 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC950,250$8.5munder 0.1%Added+939,89517 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP608,665$5.5munder 0.1%Trimmed-281,69617 Feb 2026 (the filing on sec.gov)
Invesco Ltd433,290$3.9munder 0.1%Added+23,87019 Feb 2026 (the filing on sec.gov)
Jane Street Group LLC332,471$3.0munder 0.1%Added+132,37212 Feb 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP315,000$2.8munder 0.1%Added+85,00013 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC313,695$2.8munder 0.1%Added+103,29017 Feb 2026 (the filing on sec.gov)
Bridgewater Associates LP223,166$2.0munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Woodline Partners LP200,998$1.8munder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Tudor Investment Corp189,076$1.7munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC142,735$1.3munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Millennium Management LLC126,426$1.1munder 0.1%Trimmed-481,13717 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc121,988$1.1munder 0.1%Added+29,47717 Feb 2026 (the filing on sec.gov)
PDT Partners LLC121,541$1.1m0.07%Trimmed-35,26317 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP103,100$927kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Freestone Grove Partners LP88,406$795kunder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Schonfeld Strategic Advisors LLC75,244$676kunder 0.1%Added+56,79717 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd47,957$431kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
MFS Investment Management35,398$318kunder 0.1%Newnew22 Jan 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
5 in Q3 2024 to 6 in Q2 2026

Tracked managers listing it, at least.

0510152017201820192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
NTLA by quarter
QuarterHoldersReported valueBuyersSellers
Q2 20161$223kn.a.n.a.
Q4 20161$348kn.a.n.a.
Q1 20171$1.1mn.a.n.a.
Q2 20171$2.8mn.a.n.a.
Q3 20171$9.3mn.a.n.a.
Q4 20172$48mn.a.n.a.
Q1 20183$92mn.a.n.a.
Q2 20183$149mn.a.n.a.
Q3 20183$183mn.a.n.a.
Q4 20182$94mn.a.n.a.
Q1 20191$136mn.a.n.a.
Q2 20192$136mn.a.n.a.
Q3 20192$114mn.a.n.a.
Q4 20192$129mn.a.n.a.
Q1 20202$126mn.a.n.a.
Q2 20203$260mn.a.n.a.
Q3 20203$241mn.a.n.a.
Q4 20209$709mn.a.n.a.
Q1 202110$1.1bnn.a.n.a.
Q2 202111$2.6bnn.a.n.a.
Q3 202113$2.2bnn.a.n.a.
Q4 202111$2.1bnn.a.n.a.
Q1 20228$1.0bnn.a.n.a.
Q2 20227$721mn.a.n.a.
Q3 20227$892mn.a.n.a.
Q4 20227$476mn.a.n.a.
Q1 20237$575mn.a.n.a.
Q2 20236$538mn.a.n.a.
Q3 20234$366mn.a.n.a.
Q4 20236$446m60
Q1 20247$412m51
Q2 20246$332m51
Q3 20245$310m51
Q4 20247$220m70
Q1 20253$110m21
Q2 20255$170m41
Q3 20257$333m52
Q4 20255$166m2111
Q1 20265$342m1814
Q2 20266$537m2210

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

NTLA and LLY →NTLA and JNJ →NTLA and VRTX →Choose a stock to compare with NTLA →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own NTLA, latest filings →Back to the 13F Explorer →