L3VLUP
ProSign in

INSM in the 13F filings

Insmed Inc · CUSIP 457669307

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q3 2026 · early filersQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 10 Feb 2026
Managers listing it
29
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 15 listed it in both
Shares listed
39,381,388
combined, among listed positions
Reported value
$6.9bn
combined, at the quarter end

Among the 92 comparable managers: 14 buyers (opened or added shares) and 20 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was -3,132,924.

Managers listing INSM in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

29 of 29 holders

ActionFiling
Fidelity (FMR LLC)9,927,936$1.7bn0.09%Added+746,97317 Feb 2026 (the filing on sec.gov)
Invesco Ltd7,518,338$1.3bn0.12%Added+5,514,46719 Feb 2026 (the filing on sec.gov)
Artisan Partners LP4,843,749$843m1.26%Trimmed-93,93417 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.4,350,995$757m0.42%Trimmed-1,306,46917 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc4,039,466$703m0.08%Trimmed-2,892,00017 Feb 2026 (the filing on sec.gov)
Millennium Management LLC1,311,654$228m0.10%Trimmed-1,024,45817 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC1,157,295$201munder 0.1%Trimmed-900,34617 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP962,156$167m0.24%Added+189,37617 Feb 2026 (the filing on sec.gov)
Holocene Advisors LP801,165$139m0.29%Trimmed-282,51617 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd800,555$139m0.06%Trimmed-402,22817 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP642,719$112munder 0.1%Trimmed-226,05317 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP486,138$85munder 0.1%Trimmed-231,90517 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC468,260$81munder 0.1%Added+180,97417 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP395,000$69m0.13%Added+343,70017 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP389,881$68m0.06%Trimmed-268,76613 Feb 2026 (the filing on sec.gov)
Balyasny Asset Management LLC380,561$66m0.08%Added+343,08017 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC207,869$36munder 0.1%Added+57,76327 Oct 2026 (the filing on sec.gov)
Susquehanna International Group LLP188,576$33munder 0.1%Trimmed-44,53017 Feb 2026 (the filing on sec.gov)
Woodline Partners LP130,152$23m0.09%Added+3,89017 Feb 2026 (the filing on sec.gov)
Man Group PLC118,361$21munder 0.1%Added+33,19217 Feb 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP80,087$14m0.11%Newnew17 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC66,402$12munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Freestone Grove Partners LP36,200$6.3munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC25,900$4.5munder 0.1%Trimmed-326,98712 Feb 2026 (the filing on sec.gov)
Verition Fund Management LLC16,043$2.8munder 0.1%Trimmed-12,10913 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (3)

Exited (6)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
18 in Q3 2024 to 21 in Q2 2026

Tracked managers listing it, at least.

0102030201420182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
INSM by quarter
QuarterHoldersReported valueBuyersSellers
Q3 20131$20mn.a.n.a.
Q4 20131$28mn.a.n.a.
Q1 20142$39mn.a.n.a.
Q2 20142$43mn.a.n.a.
Q3 20141$34mn.a.n.a.
Q4 20141$44mn.a.n.a.
Q1 20151$174mn.a.n.a.
Q2 20151$211mn.a.n.a.
Q3 20151$168mn.a.n.a.
Q4 20152$169mn.a.n.a.
Q3 20161$146mn.a.n.a.
Q1 20171$189mn.a.n.a.
Q2 20174$180mn.a.n.a.
Q3 20177$890mn.a.n.a.
Q4 20174$954mn.a.n.a.
Q1 20183$428mn.a.n.a.
Q2 20183$475mn.a.n.a.
Q3 20184$416mn.a.n.a.
Q4 20181$150mn.a.n.a.
Q1 20194$897mn.a.n.a.
Q2 20196$559mn.a.n.a.
Q3 20196$284mn.a.n.a.
Q4 20196$680mn.a.n.a.
Q1 20207$472mn.a.n.a.
Q2 20207$1.0bnn.a.n.a.
Q3 20209$1.2bnn.a.n.a.
Q4 20208$1.0bnn.a.n.a.
Q1 20216$816mn.a.n.a.
Q2 20216$800mn.a.n.a.
Q3 20217$803mn.a.n.a.
Q4 20217$760mn.a.n.a.
Q1 20228$680mn.a.n.a.
Q2 20227$566mn.a.n.a.
Q3 202210$379mn.a.n.a.
Q4 20228$360mn.a.n.a.
Q1 20236$282mn.a.n.a.
Q2 20236$353mn.a.n.a.
Q3 20237$415mn.a.n.a.
Q4 20238$539m45
Q1 20248$437m73
Q2 202416$2.2bn106
Q3 202418$2.3bn1010
Q4 202414$1.6bn48
Q1 202514$1.9bn94
Q2 202523$3.7bn176
Q3 202520$5.8bn109
Q4 202519$6.6bn1420
Q1 202619$7.0bn1617
Q2 202621$5.0bn2811

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

INSM and LLY →INSM and JNJ →INSM and VRTX →Choose a stock to compare with INSM →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own INSM, latest filings →Back to the 13F Explorer →