L3VLUP
Quarter end
31 Dec 2025
the date the book describes
Filed
19 Feb 2026
latest of these filings; the earliest 10 Feb 2026
Managers listing it
23
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 3 listed it in both
Shares listed
11,090,042
combined, among listed positions
Reported value
$175m
combined, at the quarter end

Among the 92 comparable managers: 18 buyers (opened or added shares) and 6 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +3,133,886.

Managers listing ENTA in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

23 of 23 holders

ActionFiling
Janus Henderson Group Ltd3,729,659$59munder 0.1%Added+1,782,74517 Feb 2026 (the filing on sec.gov)
Farallon Capital Management LLC2,772,262$44m0.19%Added+650,00017 Feb 2026 (the filing on sec.gov)
Acadian Asset Management LLC885,126$14munder 0.1%Added+18,08910 Feb 2026 (the filing on sec.gov)
Millennium Management LLC670,428$11munder 0.1%Trimmed-277,65617 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC642,200$10munder 0.1%Added+162,60012 Feb 2026 (the filing on sec.gov)
Point72 Asset Management LP438,939$6.9munder 0.1%Added+138,93917 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP385,276$6.1munder 0.1%Added+109,88713 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP285,448$4.5munder 0.1%Added+224,72617 Feb 2026 (the filing on sec.gov)
Invesco Ltd253,811$4.0munder 0.1%Added+194,11319 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC234,835$3.7munder 0.1%Added+7,99017 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.167,714$2.6munder 0.1%Trimmed-58,03017 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP143,300$2.3munder 0.1%Added+18,20017 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC93,158$1.5munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
PDT Partners LLC69,197$1.1m0.07%Trimmed-16,82517 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC65,966$1.0munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP63,219$997kunder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Arrowstreet Capital LP52,728$832kunder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Man Group PLC43,847$691kunder 0.1%Added+3,69117 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP33,740$532kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP30,000$473kunder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc14,410$228kunder 0.1%Added+4,26417 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP10,467$165kunder 0.1%Trimmed-106,83717 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)4,312$68kunder 0.1%Added+2,52717 Feb 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
2 in Q3 2024 to 3 in Q2 2026

Tracked managers listing it, at least.

035810201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
ENTA by quarter
QuarterHoldersReported valueBuyersSellers
Q3 20142$13mn.a.n.a.
Q4 20141$9.9mn.a.n.a.
Q1 20152$8.3mn.a.n.a.
Q2 20151$12mn.a.n.a.
Q3 20151$27mn.a.n.a.
Q4 20151$27mn.a.n.a.
Q1 20162$24mn.a.n.a.
Q2 20162$16mn.a.n.a.
Q3 20162$10mn.a.n.a.
Q4 20161$19mn.a.n.a.
Q1 20172$8.4mn.a.n.a.
Q3 20172$20mn.a.n.a.
Q4 20172$100mn.a.n.a.
Q1 20187$184mn.a.n.a.
Q2 20187$291mn.a.n.a.
Q3 20185$186mn.a.n.a.
Q4 20186$159mn.a.n.a.
Q1 20196$287mn.a.n.a.
Q2 20194$208mn.a.n.a.
Q3 20195$126mn.a.n.a.
Q4 20197$174mn.a.n.a.
Q1 20209$191mn.a.n.a.
Q2 20208$178mn.a.n.a.
Q3 20206$163mn.a.n.a.
Q4 20206$144mn.a.n.a.
Q1 20216$170mn.a.n.a.
Q2 20215$143mn.a.n.a.
Q3 20214$171mn.a.n.a.
Q4 20214$183mn.a.n.a.
Q1 20225$163mn.a.n.a.
Q2 20223$74mn.a.n.a.
Q3 20222$80mn.a.n.a.
Q4 20222$72mn.a.n.a.
Q1 20232$63mn.a.n.a.
Q2 20232$41mn.a.n.a.
Q3 20234$28mn.a.n.a.
Q4 20233$28m22
Q1 20243$52m21
Q2 20243$39m02
Q3 20242$31m10
Q4 20241$12m00
Q1 20252$12m20
Q2 20252$17m01
Q3 20253$37m01
Q4 20254$118m186
Q1 20262$84m1111
Q2 20263$104m713

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

ENTA and LLY →ENTA and JNJ →ENTA and VRTX →Choose a stock to compare with ENTA →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own ENTA, latest filings →Back to the 13F Explorer →