L3VLUP
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
27
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 5 listed it in both
Shares listed
30,019,461
combined, among listed positions
Reported value
$1.9bn
combined, at the quarter end

Among the 92 comparable managers: 17 buyers (opened or added shares) and 11 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +19,260.

Managers listing CYTK in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

27 of 27 holders

ActionFiling
Fidelity (FMR LLC)12,807,752$814munder 0.1%Trimmed-283,89517 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP7,937,063$504m0.09%Added+528,50217 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc1,930,119$123munder 0.1%Trimmed-436,72917 Feb 2026 (the filing on sec.gov)
Woodline Partners LP1,648,428$105m0.41%Added+70317 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC1,162,937$74munder 0.1%Trimmed-223,12817 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP753,617$48munder 0.1%Trimmed-264,18417 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP412,966$26munder 0.1%Added+177,55017 Feb 2026 (the filing on sec.gov)
ExodusPoint Capital Management LP343,144$22m0.17%Newnew17 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP337,031$21munder 0.1%Added+158,05113 Feb 2026 (the filing on sec.gov)
MFS Investment Management327,202$21munder 0.1%Trimmed-169,47122 Jan 2026 (the filing on sec.gov)
Jane Street Group LLC284,125$18munder 0.1%Newnew12 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP274,017$17munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd256,212$16munder 0.1%Added+206,64817 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC236,925$15munder 0.1%Trimmed-276,36517 Feb 2026 (the filing on sec.gov)
Millennium Management LLC225,456$14munder 0.1%Trimmed-117,07717 Feb 2026 (the filing on sec.gov)
Invesco Ltd204,878$13munder 0.1%Added+47,62919 Feb 2026 (the filing on sec.gov)
Hudson Bay Capital Management LP175,350$11munder 0.1%Trimmed-6,78113 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP174,700$11munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC172,067$11munder 0.1%Trimmed-117,90012 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.119,221$7.6munder 0.1%Added+105,61817 Feb 2026 (the filing on sec.gov)
Brevan Howard Capital Management LP101,030$6.4m0.07%Added+91,05617 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC71,378$4.5munder 0.1%Added+65,06927 Oct 2026 (the filing on sec.gov)
Moore Capital Management LP25,000$1.6munder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Walleye Capital LLC15,131$961kunder 0.1%Added+10,92813 Feb 2026 (the filing on sec.gov)
Man Group PLC11,587$736kunder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
15 in Q3 2024 to 12 in Q2 2026

Tracked managers listing it, at least.

051015202016201720192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
CYTK by quarter
QuarterHoldersReported valueBuyersSellers
Q4 20141$128kn.a.n.a.
Q4 20152$14mn.a.n.a.
Q1 20161$8.6mn.a.n.a.
Q2 20161$3.2mn.a.n.a.
Q3 20161$184kn.a.n.a.
Q1 20171$4.3mn.a.n.a.
Q2 20172$9.9mn.a.n.a.
Q3 20172$18mn.a.n.a.
Q2 20181$374kn.a.n.a.
Q3 20181$349kn.a.n.a.
Q4 20181$224kn.a.n.a.
Q1 20191$513kn.a.n.a.
Q2 20192$7.5mn.a.n.a.
Q3 20192$5.5mn.a.n.a.
Q4 20193$35mn.a.n.a.
Q1 20206$20mn.a.n.a.
Q2 20206$75mn.a.n.a.
Q3 20205$114mn.a.n.a.
Q4 20203$90mn.a.n.a.
Q1 20213$90mn.a.n.a.
Q2 20212$74mn.a.n.a.
Q3 20217$643mn.a.n.a.
Q4 202110$794mn.a.n.a.
Q1 20226$624mn.a.n.a.
Q2 202210$1.0bnn.a.n.a.
Q3 20229$1.0bnn.a.n.a.
Q4 202212$1.1bnn.a.n.a.
Q1 202311$895mn.a.n.a.
Q2 20238$781mn.a.n.a.
Q3 202310$753mn.a.n.a.
Q4 202312$2.4bn84
Q1 202415$1.8bn105
Q2 202416$1.5bn104
Q3 202415$1.5bn103
Q4 202411$1.1bn56
Q1 20259$544m71
Q2 20254$268m12
Q3 20256$1.3bn42
Q4 20258$1.5bn1711
Q1 202611$1.5bn1516
Q2 202612$1.3bn2312

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

CYTK and LLY →CYTK and JNJ →CYTK and VRTX →Choose a stock to compare with CYTK →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own CYTK, latest filings →Back to the 13F Explorer →