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AXSM in the 13F filings

Axsome Therapeutics Inc · CUSIP 05464T104

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
27 Oct 2026
latest of these filings; the earliest 10 Feb 2026
Managers listing it
29
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 5 listed it in both
Shares listed
7,833,225
combined, among listed positions
Reported value
$1.4bn
combined, at the quarter end

Among the 92 comparable managers: 15 buyers (opened or added shares) and 12 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +1,256,338.

Managers listing AXSM in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

29 of 29 holders

ActionFiling
T. Rowe Price Associates Inc1,509,870$276munder 0.1%Added+472,42217 Feb 2026 (the filing on sec.gov)
Invesco Ltd1,273,494$233munder 0.1%Added+282,93719 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP1,221,656$223munder 0.1%Trimmed-112,90417 Feb 2026 (the filing on sec.gov)
Fidelity (FMR LLC)1,181,622$216munder 0.1%Added+253,73917 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.549,113$100m0.05%Added+252,82617 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP320,568$59m0.05%Trimmed-57,45613 Feb 2026 (the filing on sec.gov)
Man Group PLC228,641$42m0.07%Trimmed-59,26717 Feb 2026 (the filing on sec.gov)
Two Sigma Advisers LP188,500$34m0.07%Newnew17 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC170,000$31munder 0.1%Added+20,00012 Feb 2026 (the filing on sec.gov)
Squarepoint Ops LLC155,000$28munder 0.1%Held013 Feb 2026 (the filing on sec.gov)
Woodline Partners LP150,864$28m0.11%Trimmed-181,00017 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP145,597$27munder 0.1%Added+137,39017 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC138,213$25munder 0.1%Trimmed-20,19317 Feb 2026 (the filing on sec.gov)
Jane Street Group LLC137,283$25munder 0.1%Added+6,43812 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC103,418$19munder 0.1%Trimmed-15,23817 Feb 2026 (the filing on sec.gov)
Neuberger Berman Group LLC69,483$13munder 0.1%Trimmed-21,69527 Oct 2026 (the filing on sec.gov)
Walleye Capital LLC60,100$11munder 0.1%Added+59,60013 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP53,140$9.7munder 0.1%Trimmed-9,92517 Feb 2026 (the filing on sec.gov)
Bridgewater Associates LP47,444$8.7munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Millennium Management LLC33,937$6.2munder 0.1%Added+28,19617 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP29,841$5.5munder 0.1%Trimmed-20,40517 Feb 2026 (the filing on sec.gov)
Quantbot Technologies LP19,396$3.5m0.12%Added+8,51910 Feb 2026 (the filing on sec.gov)
Point72 Asset Management LP17,999$3.3munder 0.1%Trimmed-71517 Feb 2026 (the filing on sec.gov)
Janus Henderson Group Ltd15,104$2.8munder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Farallon Capital Management LLC4,000$731kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Page 1 of 2

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (4)

Exited (1)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
6 in Q3 2024 to 17 in Q2 2026

Tracked managers listing it, at least.

0510152020192020202120222023202420252026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
AXSM by quarter
QuarterHoldersReported valueBuyersSellers
Q2 20171$338kn.a.n.a.
Q3 20181$62kn.a.n.a.
Q1 20192$2.7mn.a.n.a.
Q2 20192$16mn.a.n.a.
Q3 20192$11mn.a.n.a.
Q4 20197$162mn.a.n.a.
Q1 20205$48mn.a.n.a.
Q2 20203$26mn.a.n.a.
Q3 20201$2.1mn.a.n.a.
Q1 20211$2.5mn.a.n.a.
Q3 20212$12mn.a.n.a.
Q1 20222$12mn.a.n.a.
Q2 20221$2.6mn.a.n.a.
Q3 20222$37mn.a.n.a.
Q4 20224$75mn.a.n.a.
Q1 20234$146mn.a.n.a.
Q2 20236$92mn.a.n.a.
Q3 20234$78mn.a.n.a.
Q4 20234$120m32
Q1 20243$59m02
Q2 20244$65m21
Q3 20246$86m41
Q4 20243$38m20
Q1 20259$222m71
Q2 20257$139m62
Q3 20255$284m33
Q4 202512$806m1512
Q1 202612$708m1814
Q2 202617$1.4bn2411

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

AXSM and LLY →AXSM and JNJ →AXSM and VRTX →Choose a stock to compare with AXSM →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own AXSM, latest filings →Back to the 13F Explorer →