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ANNX in the 13F filings

Annexon Inc · CUSIP 03589W102

Sector · Pharmaceuticals and biotechnologyTheme · Healthcare: biopharma and medtech· L3VLUP-definedTheme · Pharmaceutical preparations
Quarter
Q2 2026Q1 2026Q4 2025Q3 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023
Quarter end
31 Dec 2025
the date the book describes
Filed
19 Feb 2026
latest of these filings; the earliest 22 Jan 2026
Managers listing it
22
at least, of 95 tracked, among listed positions
Comparable managers
92
filed both Q3 2025 and Q4 2025; 1 listed it in both
Shares listed
29,603,672
combined, among listed positions
Reported value
$149m
combined, at the quarter end

Among the 92 comparable managers: 18 buyers (opened or added shares) and 5 sellers (trimmed or exited), at least, among listed positions. Their net change in shares was +6,614,586.

Managers listing ANNX in Q4 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q3 2025, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

22 of 22 holders

ActionFiling
Fidelity (FMR LLC)10,222,470$51munder 0.1%Trimmed-858,69317 Feb 2026 (the filing on sec.gov)
Woodline Partners LP4,000,074$20m0.08%Added+1,361,79917 Feb 2026 (the filing on sec.gov)
Balyasny Asset Management LLC3,299,256$17munder 0.1%Added+2,001,99617 Feb 2026 (the filing on sec.gov)
Millennium Management LLC2,836,857$14munder 0.1%Added+14,03417 Feb 2026 (the filing on sec.gov)
D. E. Shaw & Co.1,046,221$5.3munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Invesco Ltd972,449$4.9munder 0.1%Added+770,50419 Feb 2026 (the filing on sec.gov)
MFS Investment Management903,439$4.5munder 0.1%Trimmed-76,84622 Jan 2026 (the filing on sec.gov)
Acadian Asset Management LLC861,245$4.3munder 0.1%Added+328,88210 Feb 2026 (the filing on sec.gov)
Renaissance Technologies LLC802,600$4.0munder 0.1%Added+49,02112 Feb 2026 (the filing on sec.gov)
AQR Capital Management LLC776,307$3.9munder 0.1%Added+202,18417 Feb 2026 (the filing on sec.gov)
Schonfeld Strategic Advisors LLC522,846$2.6munder 0.1%Added+310,62717 Feb 2026 (the filing on sec.gov)
Marshall Wace LLP520,998$2.6munder 0.1%Newnew13 Feb 2026 (the filing on sec.gov)
Jane Street Group LLC513,836$2.6munder 0.1%Added+294,34212 Feb 2026 (the filing on sec.gov)
T. Rowe Price Associates Inc445,074$2.2munder 0.1%Trimmed-39,70117 Feb 2026 (the filing on sec.gov)
Wellington Management Group LLP398,077$2.0munder 0.1%Newnew17 Feb 2026 (the filing on sec.gov)
Point72 Asset Management LP371,190$1.9munder 0.1%Added+281,14117 Feb 2026 (the filing on sec.gov)
Two Sigma Investments LP332,038$1.7munder 0.1%Added+52,90417 Feb 2026 (the filing on sec.gov)
Citadel Advisors LLC275,294$1.4munder 0.1%Added+107,79417 Feb 2026 (the filing on sec.gov)
Susquehanna International Group LLP185,508$931kunder 0.1%Added+34,25817 Feb 2026 (the filing on sec.gov)
AllianceBernstein LP140,740$707kunder 0.1%Held017 Feb 2026 (the filing on sec.gov)
Brevan Howard Capital Management LP123,753$621kunder 0.1%Added+29,19917 Feb 2026 (the filing on sec.gov)
Winton Group Ltd53,400$268kunder 0.1%Newnew11 Feb 2026 (the filing on sec.gov)

Largest increases and reductions, by shares

Q3 2025 to Q4 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

New (4)

Exited (2)

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
3 in Q1 2024 to 2 in Q2 2026

Tracked managers listing it, at least.

012320212022202320242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
ANNX by quarter
QuarterHoldersReported valueBuyersSellers
Q3 20203$47mn.a.n.a.
Q4 20201$39mn.a.n.a.
Q1 20212$48mn.a.n.a.
Q2 20211$31mn.a.n.a.
Q3 20212$41mn.a.n.a.
Q4 20211$5.3mn.a.n.a.
Q1 20221$698kn.a.n.a.
Q2 20222$2.0mn.a.n.a.
Q3 20221$7.8mn.a.n.a.
Q1 20232$2.2mn.a.n.a.
Q2 20231$2.5mn.a.n.a.
Q3 20231$3.5mn.a.n.a.
Q4 20231$9.1m10
Q1 20243$58m30
Q2 20242$49m20
Q3 20243$57m12
Q4 20242$43m11
Q3 20251$8.0m10
Q4 20251$20m185
Q1 20262$13m1514
Q2 20262$42m1119

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

ANNX and LLY →ANNX and JNJ →ANNX and VRTX →Choose a stock to compare with ANNX →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own ANNX, latest filings →Back to the 13F Explorer →