L3VLUP
Quarter end
31 Mar 2025
the date the book describes
Filed
5 Nov 2026
latest of these filings; the earliest 7 May 2025
Managers listing it
18
at least, of 95 tracked, among listed positions
Comparable managers
95
filed both Q4 2024 and Q1 2025; 13 listed it in both
Shares listed
55,248,474
combined, among listed positions
Reported value
$14.9bn
combined, at the quarter end

Among the 95 comparable managers: 11 buyers (opened or added shares) and 7 sellers (trimmed or exited), at least, among listed positions. Their net change in shares is not known from listed positions, because at least one of them lists it in only one of the two quarters.

Managers listing ALNY in Q1 2025

Share of 13F value is the position’s reported value over everything the manager reported that quarter. The share change is against Q4 2024, and only where both filings list the position. A rise in value with no rise in shares is the price, not buying.

18 of 18 holders

ActionFiling
Capital World Investors16,749,623$4.5bn0.73%Added+149,09812 May 2025 (the filing on sec.gov)
Fidelity (FMR LLC)15,309,860$4.1bn0.26%Added+1,823,9575 Nov 2026 (the filing on sec.gov)
Capital Research Global Investors7,154,728$1.9bn0.42%Added+186,21512 May 2025 (the filing on sec.gov)
Baillie Gifford & Co3,657,607$988m0.86%Trimmed-382,6527 May 2025 (the filing on sec.gov)
T. Rowe Price Associates Inc3,505,168$946m0.12%Added+185,78314 May 2025 (the filing on sec.gov)
Dodge & Cox3,351,762$905m0.52%Trimmed-188,50014 May 2025 (the filing on sec.gov)
Wellington Management Group LLP2,610,986$705m0.14%Trimmed-1,585,63713 May 2025 (the filing on sec.gov)
AQR Capital Management LLC828,344$217m0.22%Added+14,98815 May 2025 (the filing on sec.gov)
Point72 Asset Management LP300,635$81m0.19%Newnew21 Jul 2025 (the filing on sec.gov)
D. E. Shaw & Co.289,862$78m0.07%Trimmed-73,22315 May 2025 (the filing on sec.gov)
Millennium Management LLC287,337$78munder 0.1%Trimmedn.a.15 May 2025 (the filing on sec.gov)
Two Sigma Advisers LP275,800$74m0.17%Added+197,00015 May 2025 (the filing on sec.gov)
Marshall Wace LLP268,932$73m0.09%Trimmed-109,71715 May 2025 (the filing on sec.gov)
Two Sigma Investments LP197,415$53m0.11%Added+90,29815 May 2025 (the filing on sec.gov)
Janus Henderson Group Ltd181,649$49munder 0.1%Trimmed-28,43115 May 2025 (the filing on sec.gov)
Woodline Partners LP156,464$42m0.27%Newnew15 May 2025 (the filing on sec.gov)
Voloridge Investment Management LLC62,302$17m0.06%Addedn.a.15 May 2025 (the filing on sec.gov)
Soros Fund Management LLC60,000$16m0.24%Newnew15 May 2025 (the filing on sec.gov)

Largest increases and reductions, by shares

Q4 2024 to Q1 2025, among managers that listed it in both quarters or opened it.

Increases

Reductions

New positions and exits

At least these many: a manager is shown exiting only where its own filing shows the position gone.

Exited (0)

No exit shown by a manager’s own filing.

Ownership over time

Every quarter on file. A quarter-end value moves with the price as well as with the shares held; buyers and sellers count comparable managers, by shares.
18 in Q3 2024 to 21 in Q2 2026

Tracked managers listing it, at least.

0102030402014201620182020202220242026
the quarter shown share split complete books; unmarked quarters rest on listed positionsClick a quarter to open it.
ALNY by quarter
QuarterHoldersReported valueBuyersSellers
Q2 20134$407mn.a.n.a.
Q3 20136$1.2bnn.a.n.a.
Q4 20137$1.5bnn.a.n.a.
Q1 20148$1.6bnn.a.n.a.
Q2 20146$1.7bnn.a.n.a.
Q3 20147$2.1bnn.a.n.a.
Q4 20146$2.2bnn.a.n.a.
Q1 20158$2.9bnn.a.n.a.
Q2 20156$3.3bnn.a.n.a.
Q3 20155$2.1bnn.a.n.a.
Q4 20156$2.7bnn.a.n.a.
Q1 20168$2.0bnn.a.n.a.
Q2 20167$2.0bnn.a.n.a.
Q3 20168$2.6bnn.a.n.a.
Q4 20168$1.6bnn.a.n.a.
Q1 20179$2.2bnn.a.n.a.
Q2 201714$3.8bnn.a.n.a.
Q3 201715$5.7bnn.a.n.a.
Q4 201714$6.3bnn.a.n.a.
Q1 201815$5.7bnn.a.n.a.
Q2 201815$4.4bnn.a.n.a.
Q3 201814$3.9bnn.a.n.a.
Q4 201810$3.3bnn.a.n.a.
Q1 201911$4.6bnn.a.n.a.
Q2 201916$3.8bnn.a.n.a.
Q3 201911$4.4bnn.a.n.a.
Q4 201913$6.2bnn.a.n.a.
Q1 202012$5.7bnn.a.n.a.
Q2 202015$7.7bnn.a.n.a.
Q3 202013$7.6bnn.a.n.a.
Q4 202013$6.5bnn.a.n.a.
Q1 202114$7.2bnn.a.n.a.
Q2 202113$8.8bnn.a.n.a.
Q3 202114$9.7bnn.a.n.a.
Q4 202112$8.8bnn.a.n.a.
Q1 202212$8.9bnn.a.n.a.
Q2 202213$8.1bnn.a.n.a.
Q3 202217$10.8bnn.a.n.a.
Q4 202216$13.7bnn.a.n.a.
Q1 202319$11.5bnn.a.n.a.
Q2 202316$10.6bnn.a.n.a.
Q3 202317$9.7bnn.a.n.a.
Q4 202315$10.0bn59
Q1 202415$7.3bn106
Q2 202419$12.5bn128
Q3 202418$15.1bn711
Q4 202415$12.8bn87
Q1 202518$14.9bn117
Q2 202522$18.3bn1310
Q3 202533$26.6bn258
Q4 202524$23.4bn1528
Q1 202622$17.9bn1618
Q2 202621$15.9bn1718

Compare with…

Holders over time, buyers and sellers, and the managers holding both, side by side for up to four stocks.

ALNY and LLY →ALNY and JNJ →ALNY and VRTX →Choose a stock to compare with ALNY →

How much of the picture this is

A 13F is a manager’s long US-listed equity book at a quarter end, filed up to 45 days later. It shows no shorts, cash, bonds or performance, and it is never today’s portfolio. Large books are listed to their largest positions, so a manager missing from this table may still hold a small position below that line. These are 95 tracked managers, not the institutional market.

Which funds own ALNY, latest filings →Back to the 13F Explorer →